Decision aids for localized prostate cancer in diverse minority men: Primary outcome results from a multicenter cancer care delivery trial (Alliance A191402CD)

Jon C. Tilburt, David Zahrieh, Joel E. Pacyna, Daniel G. Petereit, Judith S. Kaur, Bruce D. Rapkin, Robert L. Grubb, George J. Chang, Michael J. Morris, Evan Z. Kovac, Kara N. Babaian, Jeff A. Sloan, Ethan M. Basch, Elizabeth S. Peil, Amylou C. Dueck, Paul J. Novotny, Electra D. Paskett, Jan C. Buckner, Daniel D. Joyce, Victor M. MontoriDominick L. Frosch, Robert J. Volk, Simon P. Kim

Research output: Contribution to journalArticlepeer-review


Background: Decision aids (DAs) can improve knowledge for prostate cancer treatment. However, the relative effects of DAs delivered within the clinical encounter and in more diverse patient populations are unknown. A multicenter cluster randomized controlled trial with a 2×2 factorial design was performed to test the effectiveness of within-visit and previsit DAs for localized prostate cancer, and minority men were oversampled. Methods: The interventions were delivered in urology practices affiliated with the NCI Community Oncology Research Program Alliance Research Base. The primary outcome was prostate cancer knowledge (percent correct on a 12-item measure) assessed immediately after a urology consultation. Results: Four sites administered the previsit DA (39 patients), 4 sites administered the within-visit DA (44 patients), 3 sites administered both previsit and within-visit DAs (25 patients), and 4 sites provided usual care (50 patients). The median percent correct in prostate cancer knowledge, based on the postvisit knowledge assessment after the intervention delivery, was as follows: 75% for the pre+within-visit DA study arm, 67% for the previsit DA only arm, 58% for the within-visit DA only arm, and 58% for the usual-care arm. Neither the previsit DA nor the within-visit DA had a significant impact on patient knowledge of prostate cancer treatments at the prespecified 2.5% significance level (P =.132 and P =.977, respectively). Conclusions: DAs for localized prostate cancer treatment provided at 2 different points in the care continuum in a trial that oversampled minority men did not confer measurable gains in prostate cancer knowledge.

Original languageEnglish (US)
Pages (from-to)1242-1251
Number of pages10
Issue number6
StatePublished - Mar 15 2022


  • decision aids
  • knowledge
  • prostate cancer
  • shared decision-making

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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