Cytomegalovirus-Induced Polyarteritis Nodosa in a Liver Transplant Recipient

K. Abadeer; N. Aslam; C. Cortese; H. M. Wadei

doi:10.1111/ajt.14376

Cytomegalovirus-Induced Polyarteritis Nodosa in a Liver Transplant Recipient

K. Abadeer, N. Aslam, C. Cortese, H. M. Wadei

Nephrology and Hypertension (Internal Med)

Research output: Contribution to journal › Article › peer-review

Abstract

Polyarteritis nodosa (PAN) is a necrotizing vasculitis that has been associated with viral infections, especially hepatitis B virus. We hereby report a case of tissue-invasive cytomegalovirus (CMV)-induced PAN in a liver transplant recipient presenting with acute kidney injury and active urinary sediment. Treatment directed against both PAN and CMV resulted in improvement in kidney function, normalization of urinary indices and resolution of the CMV infection. There was no recurrence of either PAN or CMV after a 3-year follow-up period.

Original language	English (US)
Pages (from-to)	3236-3240
Number of pages	5
Journal	American Journal of Transplantation
Volume	17
Issue number	12
DOIs	https://doi.org/10.1111/ajt.14376
State	Published - Dec 2017

Keywords

clinical research/practice
infection and infectious agents
infectious disease
liver disease: infectious
liver transplantation/hepatology
vasculopathy
viral: Cytomegalovirus (CMV)

ASJC Scopus subject areas

Immunology and Allergy
Transplantation
Pharmacology (medical)

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10.1111/ajt.14376

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title = "Cytomegalovirus-Induced Polyarteritis Nodosa in a Liver Transplant Recipient",

abstract = "Polyarteritis nodosa (PAN) is a necrotizing vasculitis that has been associated with viral infections, especially hepatitis B virus. We hereby report a case of tissue-invasive cytomegalovirus (CMV)-induced PAN in a liver transplant recipient presenting with acute kidney injury and active urinary sediment. Treatment directed against both PAN and CMV resulted in improvement in kidney function, normalization of urinary indices and resolution of the CMV infection. There was no recurrence of either PAN or CMV after a 3-year follow-up period.",

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AU - Cortese, C.

AU - Wadei, H. M.

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AB - Polyarteritis nodosa (PAN) is a necrotizing vasculitis that has been associated with viral infections, especially hepatitis B virus. We hereby report a case of tissue-invasive cytomegalovirus (CMV)-induced PAN in a liver transplant recipient presenting with acute kidney injury and active urinary sediment. Treatment directed against both PAN and CMV resulted in improvement in kidney function, normalization of urinary indices and resolution of the CMV infection. There was no recurrence of either PAN or CMV after a 3-year follow-up period.

KW - clinical research/practice

KW - infection and infectious agents

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KW - liver transplantation/hepatology

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Cytomegalovirus-Induced Polyarteritis Nodosa in a Liver Transplant Recipient

Abstract

Keywords

ASJC Scopus subject areas

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