Cyclosporine nephrotoxicity without major organ transplantation

N. S. Nahman, F. G. Cosio, S. Kolkin, J. R. Mendell, H. M. Sharma

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Cyclosporine is an immunosuppressant used primarily in transplantation and more recently in the therapy of autoimmune disease. Nephrotoxicity is a well-recognized complication of cyclosporine and includes functional and anatomical damage. We report the cases of two patients given cyclosporine for immunologic diseases other than major organ transplantation. Both patients developed irreversible renal functional impairment and had renal biopsy findings consistent with chronic cyclosporine nephrotoxicity.

Original languageEnglish (US)
Pages (from-to)400-402
Number of pages3
JournalAnnals of internal medicine
Issue number3
StatePublished - 1987

ASJC Scopus subject areas

  • Internal Medicine


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