Current status of antiretroviral therapy

Zelalem Temesgen, David Warnke, Mary J. Kasten

Research output: Contribution to journalReview articlepeer-review

68 Scopus citations


At present, there are 22 FDA-approved antiretroviral agents, which are categorised into four classes of drugs. Several others are in various stages of basic and clinical development. The authors of this paper review the general characteristics of each class of antiretrovirals, as well as individual investigational agents that are in advanced clinical development. A brief synopsis of US and WHO antiretroviral treatment guidelines is also provided.

Original languageEnglish (US)
Pages (from-to)1541-1554
Number of pages14
JournalExpert Opinion on Pharmacotherapy
Issue number12
StatePublished - Aug 2006


  • Antiretroviral therapy
  • Antiretrovirals
  • Chemokine receptor antagonists
  • Entry inhibitors
  • Fusion inhibitors
  • HIV
  • Highly active antiretroviral therapy
  • Integrase inhibitors
  • Maturation inhibitors
  • Non-nucleoside analogue reverse transcriptase inhibitors
  • Nucleoside analogue reverse transcriptase inhibitors
  • Protease inhibitors
  • Treatment guidelines

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)


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