Abstract
In order to facilitate the full use of histological methods following micro-CT imaging a cryogenic micro-CT scanning method is presented. The method involves rapid removal of the rodent organ (or biopsy from a large animal) and cooling it down rapidly. Next, the specimen is placed inside a specially-designed vessel and maintained at liquid N2 temperature. This vessel consists of a double-walled copper container with a vacuum space between the walls which is evacuated. Beryllium 'windows' in the vessel walls minimize x-ray attenuation of the low energy x-ray photons. The specimen is mounted on a stainless steel rod so that the specimen can be rotated in the small angular steps required in the CT scanning process.
| Original language | English (US) |
|---|---|
| Pages (from-to) | S-39 |
| Journal | Annals of Biomedical Engineering |
| Volume | 28 |
| Issue number | SUPPL. 1 |
| State | Published - Dec 1 2000 |
| Event | 2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA Duration: Oct 12 2000 → Oct 14 2000 |
ASJC Scopus subject areas
- Biomedical Engineering