Craniotomy for anterior cranial fossa meningiomas: Historical overview

Saul F. Morales-Valero, Jamie J. Van Gompel, Ioannis Loumiotis, Giuseppe Lanzino

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


The surgical treatment of meningiomas located at the base of the anterior cranial fossa is often challenging, and the evolution of the surgical strategy to resect these tumors parallels the development of craniotomy, and neurosurgery in general, over the past century. Early successful operations to treat these tumors were pioneered by prominent figures such as Sir William Macewen and Francesco Durante. Following these early reports, Harvey Cushing made significant contributions, allowing a better understanding and treatment of meningiomas in general, but particularly those involving the anterior cranial base. Initially, large-sized unilateral or bilateral craniotomies were necessary to approach these deep-seated lesions. Technical advances such as the introduction of electrosurgery, the operating microscope, and refined microsurgical instruments allowed neurosurgeons to perform less invasive surgical procedures with better results. Today, a wide variety of surgical strategies, including endoscopic surgery and radiosurgery, are used to treat these tumors. In this review, the authors trace the evolution of craniotomy for anterior cranial fossa meningiomas.

Original languageEnglish (US)
Article numberE14
JournalNeurosurgical focus
Issue number4
StatePublished - Apr 2014


  • Anterior cranial fossa
  • Craniotomy
  • History
  • Intracranial meningiomas

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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