Cranial neuropathy associated with primary amyloidosis

Ann E. Traynor, Morie A. Gertz, Robert A. Kyle

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


We report 6 patients for whom cranial neuropathy was a major manifestation of primary amyloidosis. In 3 of the 6, multiple cranial nerves were involved. All had tissue biopsy documentation of amyloidosis. In 2, nerve biopsy also confirmed amyloidosis. All had renal involvement manifested by proteinuria. Primary systemic amyloidosis must be considered in the differential diagnosis of cranial neuropathy, especially when proteinuria is present.

Original languageEnglish (US)
Pages (from-to)451-454
Number of pages4
JournalAnnals of neurology
Issue number4
StatePublished - Apr 1991

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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