Coronary spasm and vasomotor dysfunction as a cause of MINOCA

Zachary S. Yaker; A. Michael Lincoff; Leslie Cho; Stephen G. Ellis; Khaled M. Ziada; Joseph J. Zieminski; Rajiv Gulati; Bernard J. Gersh; David Holmes; Claire E. Raphael

doi:10.4244/EIJ-D-23-00448

Coronary spasm and vasomotor dysfunction as a cause of MINOCA

Zachary S. Yaker, A. Michael Lincoff, Leslie Cho, Stephen G. Ellis, Khaled M. Ziada, Joseph J. Zieminski, Rajiv Gulati, Bernard J. Gersh, David Holmes, Claire E. Raphael

Cardiovascular Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Increasing evidence has shown that coronary spasm and vasomotor dysfunction may be the underlying cause in more than half of myocardial infarctions with non-obstructive coronary arteries (MINOCA) as well as an important cause of chronic chest pain in the outpatient setting. We review the contemporary understanding of coronary spasm and related vasomotor dysfunction of the coronary arteries, the pathophysiology and prognosis, and current and emerging approaches to diagnosis and evidence-based treatment.

Original language	English (US)
Pages (from-to)	e123-e134
Journal	EuroIntervention
Volume	20
Issue number	2
DOIs	https://doi.org/10.4244/EIJ-D-23-00448
State	Published - Jan 2024

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.4244/EIJ-D-23-00448

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abstract = "Increasing evidence has shown that coronary spasm and vasomotor dysfunction may be the underlying cause in more than half of myocardial infarctions with non-obstructive coronary arteries (MINOCA) as well as an important cause of chronic chest pain in the outpatient setting. We review the contemporary understanding of coronary spasm and related vasomotor dysfunction of the coronary arteries, the pathophysiology and prognosis, and current and emerging approaches to diagnosis and evidence-based treatment.",

author = "Yaker, {Zachary S.} and Lincoff, {A. Michael} and Leslie Cho and Ellis, {Stephen G.} and Ziada, {Khaled M.} and Zieminski, {Joseph J.} and Rajiv Gulati and Gersh, {Bernard J.} and David Holmes and Raphael, {Claire E.}",

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AU - Yaker, Zachary S.

AU - Lincoff, A. Michael

AU - Cho, Leslie

AU - Ellis, Stephen G.

AU - Ziada, Khaled M.

AU - Zieminski, Joseph J.

AU - Gulati, Rajiv

AU - Gersh, Bernard J.

AU - Holmes, David

AU - Raphael, Claire E.

PY - 2024/1

Y1 - 2024/1

N2 - Increasing evidence has shown that coronary spasm and vasomotor dysfunction may be the underlying cause in more than half of myocardial infarctions with non-obstructive coronary arteries (MINOCA) as well as an important cause of chronic chest pain in the outpatient setting. We review the contemporary understanding of coronary spasm and related vasomotor dysfunction of the coronary arteries, the pathophysiology and prognosis, and current and emerging approaches to diagnosis and evidence-based treatment.

AB - Increasing evidence has shown that coronary spasm and vasomotor dysfunction may be the underlying cause in more than half of myocardial infarctions with non-obstructive coronary arteries (MINOCA) as well as an important cause of chronic chest pain in the outpatient setting. We review the contemporary understanding of coronary spasm and related vasomotor dysfunction of the coronary arteries, the pathophysiology and prognosis, and current and emerging approaches to diagnosis and evidence-based treatment.

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JO - EuroIntervention

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Coronary spasm and vasomotor dysfunction as a cause of MINOCA

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