Contrast Enhanced Spectral Mammography: A Review

Bhavika K. Patel, M. B.I. Lobbes, John Lewin

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


Contrast-enhanced spectral mammography (CESM) provides low-energy 2D mammographic images comparable to standard digital mammography and a post-contrast recombined image to assess tumor neovascularity similar to magnetic resonance imaging (MRI). The utilization of CESM in the United States is currently low but could increase rapidly given many potential indications for clinical use. This article discusses historical background and literature review of indications and diagnostic accuracy of CESM to date. CESM is a growing technique for breast cancer detection and diagnosis that has levels of sensitivity and specificity on par with contrast-enhanced breast MRI. Because of its similar performance and ease of implementation, CESM is being adopted for multiple indications previously reserved for MRI, such as problem-solving, disease extent in newly diagnosed patients, and evaluating the treatment response of neoadjuvant chemotherapy.

Original languageEnglish (US)
Pages (from-to)70-79
Number of pages10
JournalSeminars in Ultrasound, CT and MRI
Issue number1
StatePublished - Feb 2018

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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