TY - JOUR
T1 - Contemporary Revision Total Knee Arthroplasty in Patients Younger Than 50 Years
T2 - 1 in 3 Risk of Re-Revision by 10 Years
AU - Chalmers, Brian P.
AU - Pallante, Graham D.
AU - Sierra, Rafael J.
AU - Lewallen, David G.
AU - Pagnano, Mark W.
AU - Trousdale, Robert T.
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/7
Y1 - 2019/7
N2 - Background: There is a paucity of literature on contemporary aseptic revision total knee arthroplasty in patients ≤50 years. We sought to determine risk factors for failure in this population, with specific emphasis on survivorship free of (1) all-cause re-revision and (2) re-revision for instability. Methods: We retrospectively reviewed 135 nononcologic revision total knee arthroplasties (TKAs) performed from 2000 to 2012 in patients ≤50 years. Mean age was 43 years, and mean body mass index was 31 kg/m2. Mean follow-up was 7 years. There were 99 (73%) first-time revisions, and 36 (27%) with prior revisions. Indications for revision included instability (47%), aseptic loosening (29%), and arthrofibrosis (9%). Multivariate Cox regression analysis was used to identify risk factors. Results: Survivorship free of all-cause re-revision was 66% at 10 years, with multiply revised TKAs (hazard ratio [HR] = 2.6, P = .008) having the poorest survivorship. Forty-three (32%) TKAs underwent re-revision including 10 (7%) for periprosthetic joint infection. Survivorship free of re-revision for instability was 88% at 10 years, with revision for instability (HR = 19, P = .03), male gender (HR = 3.0, P = .05), and multiply revised TKAs (HR = 3.5, P = .03) having poorer survival. Of the 64 TKAs revised for instability, 24 (38%) underwent re-revision, including 14 (22%) for recurrent instability. Conclusion: Patients ≤50 years undergoing contemporary aseptic revision TKA had a 1 in 3 risk of re-revision. Patients specifically revised for instability or had prior TKA revisions had the highest risk of re-revision at 10 years. Level of Evidence: IV.
AB - Background: There is a paucity of literature on contemporary aseptic revision total knee arthroplasty in patients ≤50 years. We sought to determine risk factors for failure in this population, with specific emphasis on survivorship free of (1) all-cause re-revision and (2) re-revision for instability. Methods: We retrospectively reviewed 135 nononcologic revision total knee arthroplasties (TKAs) performed from 2000 to 2012 in patients ≤50 years. Mean age was 43 years, and mean body mass index was 31 kg/m2. Mean follow-up was 7 years. There were 99 (73%) first-time revisions, and 36 (27%) with prior revisions. Indications for revision included instability (47%), aseptic loosening (29%), and arthrofibrosis (9%). Multivariate Cox regression analysis was used to identify risk factors. Results: Survivorship free of all-cause re-revision was 66% at 10 years, with multiply revised TKAs (hazard ratio [HR] = 2.6, P = .008) having the poorest survivorship. Forty-three (32%) TKAs underwent re-revision including 10 (7%) for periprosthetic joint infection. Survivorship free of re-revision for instability was 88% at 10 years, with revision for instability (HR = 19, P = .03), male gender (HR = 3.0, P = .05), and multiply revised TKAs (HR = 3.5, P = .03) having poorer survival. Of the 64 TKAs revised for instability, 24 (38%) underwent re-revision, including 14 (22%) for recurrent instability. Conclusion: Patients ≤50 years undergoing contemporary aseptic revision TKA had a 1 in 3 risk of re-revision. Patients specifically revised for instability or had prior TKA revisions had the highest risk of re-revision at 10 years. Level of Evidence: IV.
KW - aseptic loosening
KW - complications
KW - instability
KW - revision
KW - total knee arthroplasty
KW - young age
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U2 - 10.1016/j.arth.2019.02.001
DO - 10.1016/j.arth.2019.02.001
M3 - Article
C2 - 30824295
AN - SCOPUS:85061974615
SN - 0883-5403
VL - 34
SP - S266-S270
JO - Journal of Arthroplasty
JF - Journal of Arthroplasty
IS - 7
ER -