Consult and procedure incidence outcomes following establishment of a fertility preservation program for children with cancer

Supriya Behl, Vidhu B. Joshi, Reda S. Hussein, David L. Walker, Kari L. Lampat, Anthony G. Krenik, Kathrynne M. Barud, Jolene R. Fredrickson, Terri M. Galanits, Katherine J. Rian, Adriana M. Delgado, Julia H. Byrne, Dean Potter, Siobhan T. Pittock, Carola A.S. Arndt, Yulian Zhao, Patricio C. Gargollo, Candace F. Granberg, Zaraq Khan, Asma J. Chattha

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Purpose: Fertility is a quality of life outcome adversely affected by cancer therapy. Many childhood cancer patients, however, are not offered options to preserve their fertility. Providers acknowledge difficulty discussing impaired fertility to patients due to lack of knowledge of available options. Our objective was to review the impact of a pediatric multidisciplinary fertility preservation program on providers’ fertility preservation counseling and discussion of options. Methods: A retrospective medical chart review was conducted for pediatric cancer patients prior to and following program establishment. Fertility preservation discussions, consults, and incidence were noted. Following filtering and stratification, 198 and 237 patients were seen prior to and following program establishment, respectively. Results: Following program establishment, provider–patient discussions of impaired fertility (p = 0.007), fertility preservation consults (p = 0.01), and incidence of fertility preservation procedures (p < 0.001) increased among patients. Furthermore, the number of patients who received fertility preservation consults after receiving gonadotoxic treatment decreased (p < 0.001). This trend was particularly noted in pre-pubertal and female patients, for whom fertility preservation options are limited without an established program. Conclusion: The establishment of a formal program greatly improved access to fertility preservation consults and procedures in children with cancer.

Original languageEnglish (US)
Pages (from-to)495-501
Number of pages7
JournalJournal of Assisted Reproduction and Genetics
Issue number2
StatePublished - Feb 2021


  • Childhood cancer
  • Gonadotoxic treatment
  • Gynecology
  • Infertility
  • Pediatrics
  • Urology

ASJC Scopus subject areas

  • Reproductive Medicine
  • Genetics
  • Obstetrics and Gynecology
  • Developmental Biology
  • Genetics(clinical)


Dive into the research topics of 'Consult and procedure incidence outcomes following establishment of a fertility preservation program for children with cancer'. Together they form a unique fingerprint.

Cite this