Consensus-based technical recommendations for clinical translation of renal BOLD MRI

Octavia Bane; Iosif A. Mendichovszky; Bastien Milani; Ilona A. Dekkers; Jean Francois Deux; Per Eckerbom; Nicolas Grenier; Michael E. Hall; Tsutomu Inoue; Christoffer Laustsen; Lilach O. Lerman; Chunlei Liu; Glen Morrell; Michael Pedersen; Menno Pruijm; Elizabeth A. Sadowski; Erdmann Seeliger; Kanishka Sharma; Harriet Thoeny; Peter Vermathen; Zhen J. Wang; Zbigniew Serafin; Jeff L. Zhang; Susan T. Francis; Steven Sourbron; Andreas Pohlmann; Sean B. Fain; Pottumarthi V. Prasad

doi:10.1007/s10334-019-00802-x

Consensus-based technical recommendations for clinical translation of renal BOLD MRI

Octavia Bane, Iosif A. Mendichovszky, Bastien Milani, Ilona A. Dekkers, Jean Francois Deux, Per Eckerbom, Nicolas Grenier, Michael E. Hall, Tsutomu Inoue, Christoffer Laustsen, Lilach O. Lerman, Chunlei Liu, Glen Morrell, Michael Pedersen, Menno Pruijm, Elizabeth A. Sadowski, Erdmann Seeliger, Kanishka Sharma, Harriet Thoeny, Peter VermathenZhen J. Wang, Zbigniew Serafin, Jeff L. Zhang, Susan T. Francis, Steven Sourbron, Andreas Pohlmann, Sean B. Fain, Pottumarthi V. Prasad

Nephrology and Hypertension

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

Harmonization of acquisition and analysis protocols is an important step in the validation of BOLD MRI as a renal biomarker. This harmonization initiative provides technical recommendations based on a consensus report with the aim to move towards standardized protocols that facilitate clinical translation and comparison of data across sites. We used a recently published systematic review paper, which included a detailed summary of renal BOLD MRI technical parameters and areas of investigation in its supplementary material, as the starting point in developing the survey questionnaires for seeking consensus. Survey data were collected via the Delphi consensus process from 24 researchers on renal BOLD MRI exam preparation, data acquisition, data analysis, and interpretation. Consensus was defined as ≥ 75% unanimity in response. Among 31 survey questions, 14 achieved consensus resolution, 12 showed clear respondent preference (65–74% agreement), and 5 showed equal (50/50%) split in opinion among respondents. Recommendations for subject preparation, data acquisition, processing and reporting are given based on the survey results and review of the literature. These technical recommendations are aimed towards increased inter-site harmonization, a first step towards standardization of renal BOLD MRI protocols across sites. We expect this to be an iterative process updated dynamically based on progress in the field.

Original language	English (US)
Pages (from-to)	199-215
Number of pages	17
Journal	Magnetic Resonance Materials in Physics, Biology and Medicine
Volume	33
Issue number	1
DOIs	https://doi.org/10.1007/s10334-019-00802-x
State	Published - Feb 1 2020

Keywords

BOLD MRI
Biomarkers
Consensus
Imaging
Kidney
Standardization

ASJC Scopus subject areas

Biophysics
Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging

Access to Document

10.1007/s10334-019-00802-x

Cite this

Bane, O., Mendichovszky, I. A., Milani, B., Dekkers, I. A., Deux, J. F., Eckerbom, P., Grenier, N., Hall, M. E., Inoue, T., Laustsen, C., Lerman, L. O., Liu, C., Morrell, G., Pedersen, M., Pruijm, M., Sadowski, E. A., Seeliger, E., Sharma, K., Thoeny, H., ... Prasad, P. V. (2020). Consensus-based technical recommendations for clinical translation of renal BOLD MRI. Magnetic Resonance Materials in Physics, Biology and Medicine, 33(1), 199-215. https://doi.org/10.1007/s10334-019-00802-x

Bane, O, Mendichovszky, IA, Milani, B, Dekkers, IA, Deux, JF, Eckerbom, P, Grenier, N, Hall, ME, Inoue, T, Laustsen, C, Lerman, LO, Liu, C, Morrell, G, Pedersen, M, Pruijm, M, Sadowski, EA, Seeliger, E, Sharma, K, Thoeny, H, Vermathen, P, Wang, ZJ, Serafin, Z, Zhang, JL, Francis, ST, Sourbron, S, Pohlmann, A, Fain, SB & Prasad, PV 2020, 'Consensus-based technical recommendations for clinical translation of renal BOLD MRI', Magnetic Resonance Materials in Physics, Biology and Medicine, vol. 33, no. 1, pp. 199-215. https://doi.org/10.1007/s10334-019-00802-x

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title = "Consensus-based technical recommendations for clinical translation of renal BOLD MRI",

abstract = "Harmonization of acquisition and analysis protocols is an important step in the validation of BOLD MRI as a renal biomarker. This harmonization initiative provides technical recommendations based on a consensus report with the aim to move towards standardized protocols that facilitate clinical translation and comparison of data across sites. We used a recently published systematic review paper, which included a detailed summary of renal BOLD MRI technical parameters and areas of investigation in its supplementary material, as the starting point in developing the survey questionnaires for seeking consensus. Survey data were collected via the Delphi consensus process from 24 researchers on renal BOLD MRI exam preparation, data acquisition, data analysis, and interpretation. Consensus was defined as ≥ 75% unanimity in response. Among 31 survey questions, 14 achieved consensus resolution, 12 showed clear respondent preference (65–74% agreement), and 5 showed equal (50/50%) split in opinion among respondents. Recommendations for subject preparation, data acquisition, processing and reporting are given based on the survey results and review of the literature. These technical recommendations are aimed towards increased inter-site harmonization, a first step towards standardization of renal BOLD MRI protocols across sites. We expect this to be an iterative process updated dynamically based on progress in the field.",

keywords = "BOLD MRI, Biomarkers, Consensus, Imaging, Kidney, Standardization",

author = "Octavia Bane and Mendichovszky, {Iosif A.} and Bastien Milani and Dekkers, {Ilona A.} and Deux, {Jean Francois} and Per Eckerbom and Nicolas Grenier and Hall, {Michael E.} and Tsutomu Inoue and Christoffer Laustsen and Lerman, {Lilach O.} and Chunlei Liu and Glen Morrell and Michael Pedersen and Menno Pruijm and Sadowski, {Elizabeth A.} and Erdmann Seeliger and Kanishka Sharma and Harriet Thoeny and Peter Vermathen and Wang, {Zhen J.} and Zbigniew Serafin and Zhang, {Jeff L.} and Francis, {Susan T.} and Steven Sourbron and Andreas Pohlmann and Fain, {Sean B.} and Prasad, {Pottumarthi V.}",

note = "Funding Information: The article is based upon work from COST Action Magnetic Resonance Imaging Biomarkers for Chronic Kidney Disease (PARENCHIMA, COST Action CA 16103, www.renalmri.org ), supported by COST (European Cooperation in Science and Technology), www.cost.eu . O.B. received funding (2016-2018) from NIH NIDDK individual fellowship 1F32DK109591. K.S. and S.S. received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 115974. S.T.F, I.M and S.S receive funding from the Medical Research Council [grant number MR/R02264X/1]. A.P. and E.S. receive funding from the German Research Council (DFG; Collaborative Research Centre SFB 1365 Renoprotection). M.P. receives funding from the Swiss National Science Foundation (FN 320030-169191). H.C.T: receives funding from Swiss National Science Foundation NIZCOZO_177140/1. P.V.P. receives funding from NIDDK R01 DK093793 and R01 DK106557. Funding Information: The article is based upon work from COST Action Magnetic Resonance Imaging Biomarkers for Chronic Kidney Disease (PARENCHIMA, COST Action CA 16103, www.renalmri.org), supported by COST (European Cooperation in Science and Technology), www.cost.eu. O.B. received funding (2016-2018) from NIH NIDDK individual fellowship 1F32DK109591. K.S. and S.S. received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 115974. S.T.F, I.M and S.S receive funding from the Medical Research Council [grant number MR/R02264X/1]. A.P. and E.S. receive funding from the German Research Council (DFG; Collaborative Research Centre SFB 1365 Renoprotection). M.P. receives funding from the Swiss National Science Foundation (FN 320030-169191). H.C.T: receives funding from Swiss National Science Foundation NIZCOZO_177140/1. P.V.P. receives funding from NIDDK R01 DK093793 and R01 DK106557. Publisher Copyright: {\textcopyright} 2019, The Author(s).",

year = "2020",

month = feb,

day = "1",

doi = "10.1007/s10334-019-00802-x",

language = "English (US)",

volume = "33",

pages = "199--215",

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TY - JOUR

T1 - Consensus-based technical recommendations for clinical translation of renal BOLD MRI

AU - Bane, Octavia

AU - Mendichovszky, Iosif A.

AU - Milani, Bastien

AU - Dekkers, Ilona A.

AU - Deux, Jean Francois

AU - Eckerbom, Per

AU - Grenier, Nicolas

AU - Hall, Michael E.

AU - Inoue, Tsutomu

AU - Laustsen, Christoffer

AU - Lerman, Lilach O.

AU - Liu, Chunlei

AU - Morrell, Glen

AU - Pedersen, Michael

AU - Pruijm, Menno

AU - Sadowski, Elizabeth A.

AU - Seeliger, Erdmann

AU - Sharma, Kanishka

AU - Thoeny, Harriet

AU - Vermathen, Peter

AU - Wang, Zhen J.

AU - Serafin, Zbigniew

AU - Zhang, Jeff L.

AU - Francis, Susan T.

AU - Sourbron, Steven

AU - Pohlmann, Andreas

AU - Fain, Sean B.

AU - Prasad, Pottumarthi V.

N1 - Funding Information: The article is based upon work from COST Action Magnetic Resonance Imaging Biomarkers for Chronic Kidney Disease (PARENCHIMA, COST Action CA 16103, www.renalmri.org ), supported by COST (European Cooperation in Science and Technology), www.cost.eu . O.B. received funding (2016-2018) from NIH NIDDK individual fellowship 1F32DK109591. K.S. and S.S. received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 115974. S.T.F, I.M and S.S receive funding from the Medical Research Council [grant number MR/R02264X/1]. A.P. and E.S. receive funding from the German Research Council (DFG; Collaborative Research Centre SFB 1365 Renoprotection). M.P. receives funding from the Swiss National Science Foundation (FN 320030-169191). H.C.T: receives funding from Swiss National Science Foundation NIZCOZO_177140/1. P.V.P. receives funding from NIDDK R01 DK093793 and R01 DK106557. Funding Information: The article is based upon work from COST Action Magnetic Resonance Imaging Biomarkers for Chronic Kidney Disease (PARENCHIMA, COST Action CA 16103, www.renalmri.org), supported by COST (European Cooperation in Science and Technology), www.cost.eu. O.B. received funding (2016-2018) from NIH NIDDK individual fellowship 1F32DK109591. K.S. and S.S. received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 115974. S.T.F, I.M and S.S receive funding from the Medical Research Council [grant number MR/R02264X/1]. A.P. and E.S. receive funding from the German Research Council (DFG; Collaborative Research Centre SFB 1365 Renoprotection). M.P. receives funding from the Swiss National Science Foundation (FN 320030-169191). H.C.T: receives funding from Swiss National Science Foundation NIZCOZO_177140/1. P.V.P. receives funding from NIDDK R01 DK093793 and R01 DK106557. Publisher Copyright: © 2019, The Author(s).

PY - 2020/2/1

Y1 - 2020/2/1

N2 - Harmonization of acquisition and analysis protocols is an important step in the validation of BOLD MRI as a renal biomarker. This harmonization initiative provides technical recommendations based on a consensus report with the aim to move towards standardized protocols that facilitate clinical translation and comparison of data across sites. We used a recently published systematic review paper, which included a detailed summary of renal BOLD MRI technical parameters and areas of investigation in its supplementary material, as the starting point in developing the survey questionnaires for seeking consensus. Survey data were collected via the Delphi consensus process from 24 researchers on renal BOLD MRI exam preparation, data acquisition, data analysis, and interpretation. Consensus was defined as ≥ 75% unanimity in response. Among 31 survey questions, 14 achieved consensus resolution, 12 showed clear respondent preference (65–74% agreement), and 5 showed equal (50/50%) split in opinion among respondents. Recommendations for subject preparation, data acquisition, processing and reporting are given based on the survey results and review of the literature. These technical recommendations are aimed towards increased inter-site harmonization, a first step towards standardization of renal BOLD MRI protocols across sites. We expect this to be an iterative process updated dynamically based on progress in the field.

AB - Harmonization of acquisition and analysis protocols is an important step in the validation of BOLD MRI as a renal biomarker. This harmonization initiative provides technical recommendations based on a consensus report with the aim to move towards standardized protocols that facilitate clinical translation and comparison of data across sites. We used a recently published systematic review paper, which included a detailed summary of renal BOLD MRI technical parameters and areas of investigation in its supplementary material, as the starting point in developing the survey questionnaires for seeking consensus. Survey data were collected via the Delphi consensus process from 24 researchers on renal BOLD MRI exam preparation, data acquisition, data analysis, and interpretation. Consensus was defined as ≥ 75% unanimity in response. Among 31 survey questions, 14 achieved consensus resolution, 12 showed clear respondent preference (65–74% agreement), and 5 showed equal (50/50%) split in opinion among respondents. Recommendations for subject preparation, data acquisition, processing and reporting are given based on the survey results and review of the literature. These technical recommendations are aimed towards increased inter-site harmonization, a first step towards standardization of renal BOLD MRI protocols across sites. We expect this to be an iterative process updated dynamically based on progress in the field.

KW - BOLD MRI

KW - Biomarkers

KW - Consensus

KW - Imaging

KW - Kidney

KW - Standardization

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JO - Magnetic Resonance Materials in Physics, Biology and Medicine

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Consensus-based technical recommendations for clinical translation of renal BOLD MRI

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