Compression of NMR data. Application to two-dimensional NMR spectroscopy and imaging

Zsolt Zolnai, Slobodan Macura, John L. Markley

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The important information in a high-resolution two-dimensional NMR spectrum or 2D NMR image is localized in a small fraction of the overall data block. Hence data files should be subject to compression by suitable manipulation. We propose two methods for data compression: elimination of background noise and logarithmic scaling of the data. By combining the two methods, one can obtain a compression factor of 30 or more without significant loss of spectral information content. The method is particularly suitable for the storage of massive data sets. One or more two-dimensional spectra can be reduced and stored on one floppy disk. These methods and their versatility are demonstrated via compression of two-dimensional NMR spectra of a small protein (turkey ovomucoid third domain) and via compression of the NMR image of a phantom.

Original languageEnglish (US)
Pages (from-to)60-70
Number of pages11
JournalJournal of Magnetic Resonance (1969)
Issue number1
StatePublished - Oct 15 1988


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