TY - CHAP
T1 - Compositional analysis of the human microbiome in cancer research
AU - Morales, Elisa
AU - Chen, Jun
AU - Greathouse, K. Leigh
N1 - Publisher Copyright:
© Springer Science+Business Media, LLC, part of Springer Nature 2019.
PY - 2019
Y1 - 2019
N2 - Gut microbial composition has shown to be associated with obesity, diabetes mellitus, inflammatory bowel disease, colitis, autoimmune disorders, and cancer, among other diseases. Microbiome research has significantly evolved through the years and continues to advance as we develop new and better strategies to more accurately measure its composition and function. Careful selection of study design, inclusion and exclusion criteria of participants, and methodology are paramount to accurately analyze microbial structure. Here we present the most up-to-date available information on methods for gut microbial collection and analysis.
AB - Gut microbial composition has shown to be associated with obesity, diabetes mellitus, inflammatory bowel disease, colitis, autoimmune disorders, and cancer, among other diseases. Microbiome research has significantly evolved through the years and continues to advance as we develop new and better strategies to more accurately measure its composition and function. Careful selection of study design, inclusion and exclusion criteria of participants, and methodology are paramount to accurately analyze microbial structure. Here we present the most up-to-date available information on methods for gut microbial collection and analysis.
KW - Cancer research
KW - Gut microbiota
KW - Metagenomic sequencing
KW - Taxonomic classification
UR - http://www.scopus.com/inward/record.url?scp=85061135345&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85061135345&partnerID=8YFLogxK
U2 - 10.1007/978-1-4939-9027-6_16
DO - 10.1007/978-1-4939-9027-6_16
M3 - Chapter
C2 - 30725462
AN - SCOPUS:85061135345
T3 - Methods in Molecular Biology
SP - 299
EP - 335
BT - Methods in Molecular Biology
PB - Humana Press Inc.
ER -