TY - JOUR
T1 - Complications of Myeloma Therapy
AU - Dispenzieri, Angela
N1 - Funding Information:
Angela Dispenzieri is supported in part by grants CA125614, CA062242, CA107476, CA15083, and CA11345 from the National Cancer Institute.
PY - 2007/12
Y1 - 2007/12
N2 - The advent of new therapies for multiple myeloma brings new hope for patients but also new side effects. Emerging information about the risks of supportive care therapies, including long-term, high-intensity bisphosphonate use and erythropoiesis-stimulating agents, is examined. As the number of drugs in the myeloma armamentarium grows, so does the list of possible side effects and interactions. With current progress, not only are there more complications to consider but patients are also living longer and the risk for delayed complications is becoming more relevant. The author provides perspective about the risks for the most active and commonly used single-agent and combination myeloma therapies.
AB - The advent of new therapies for multiple myeloma brings new hope for patients but also new side effects. Emerging information about the risks of supportive care therapies, including long-term, high-intensity bisphosphonate use and erythropoiesis-stimulating agents, is examined. As the number of drugs in the myeloma armamentarium grows, so does the list of possible side effects and interactions. With current progress, not only are there more complications to consider but patients are also living longer and the risk for delayed complications is becoming more relevant. The author provides perspective about the risks for the most active and commonly used single-agent and combination myeloma therapies.
UR - http://www.scopus.com/inward/record.url?scp=35748954667&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=35748954667&partnerID=8YFLogxK
U2 - 10.1016/j.hoc.2007.08.002
DO - 10.1016/j.hoc.2007.08.002
M3 - Review article
C2 - 17996597
AN - SCOPUS:35748954667
SN - 0889-8588
VL - 21
SP - 1247
EP - 1273
JO - Hematology/Oncology Clinics of North America
JF - Hematology/Oncology Clinics of North America
IS - 6
ER -