Abstract
Lung-only metastatic prostate cancer can be seen in 4.6% of patients and historically patients with visceral metastastic disease are considered high risk. In order to determine survival outcomes in this patient population, we conducted a restrospective review of patients with metastatic hormone sensitive prostate cancer with lung-only metastases. In this single institution review, 10 patients were identified with 8 achieving a complete response and 2 achieving a partial response when treated with androgen deprevation therapy (ADT) with or without metastastetomy. The median progression free survival was 64.4 months with 8 of these patients (80%) with ongoing complete response at time of follow-up. Lung-only metastases may serve as a good prognostic characteristic which will allow the clinician to treat with ADT alone with or without surgery to minimize treatment realted toxicity and still offer the ability to achieve a complete response with prolonged survival.
Original language | English (US) |
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Pages (from-to) | e485-e489 |
Journal | Clinical Genitourinary Cancer |
Volume | 20 |
Issue number | 6 |
DOIs | |
State | Published - Dec 2022 |
Keywords
- Androgen deprivation therapy (ADT)
- Complete response
- Lung metastases
- Lung-only metastatic prostate cancer
- Metastatic hormone sensitive prostate cancer
- Oligometastatic prostate cancer
ASJC Scopus subject areas
- Oncology
- Urology