Comparison of respondents and nonrespondents in an osteoporosis study

C. Mary Beard, Ann W. Lane, W. Michael O'Fallon, B. Lawrence Riggs, L. Joseph Melton

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


We attempted to enroll an age-stratified random sample of Rochester, Minnesota women ≥ 30 years of age in a population-based prospective study of the determinants of bone loss. Using the resources of the Rochester Epidemiology Project, 541 women were contacted and 305 agreed to participate. Of 236 nonrespondents, 38 were ineligible and 198 refused to participate resulting in a 61% response rate for eligible subjects. We reviewed community medical records for respondents and nonrespondents (including ineligibles) to determine whether the two groups differed with regard to variables that might be important in osteoporosis research. There was little difference between respondents and nonrespondents for a history of cigarette smoking, hyperthyroidism, thyroidectomy, or age-related fractures. Respondents survived better, were less likely to be obese or have renal failure, and more likely to have had an oophorectomy and consume alcohol (P < 0.01). These data suggest that nonrespondents were less healthy than respondents.

Original languageEnglish (US)
Pages (from-to)398-403
Number of pages6
JournalAnnals of Epidemiology
Issue number5
StatePublished - Sep 1994


  • Response bias
  • epidemiology
  • nonresponders
  • osteoporosis
  • responders

ASJC Scopus subject areas

  • Epidemiology


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