TY - JOUR
T1 - Comparison of covered stents versus bare metal stents for treatment of chronic atherosclerotic mesenteric arterial disease
AU - Oderich, Gustavo S.
AU - Erdoes, Luke S.
AU - Lesar, Christopher
AU - Mendes, Bernardo C.
AU - Gloviczki, Peter
AU - Cha, Stephen
AU - Duncan, Audra A.
AU - Bower, Thomas C.
PY - 2013/11
Y1 - 2013/11
N2 - Objective: To compare outcomes of mesenteric angioplasty and stenting using iCAST covered stents (CS; Atrium, Hudson, NH) or bare metal stents (BMS) in patients with chronic mesenteric ischemia (CMI). Methods: We reviewed the clinical data of 225 patients (65 male and 160 female; mean age, 72 ± 12 years) treated for CMI at two academic centers (2000-2010). Outcomes were analyzed in patients who had primary intervention or reintervention using BMS (n = 164 patients/197 vessels) or CS (n = 61 patients/67 vessels). End points were freedom from restenosis, symptom recurrence, reinterventions, and patency rates. Results: Patients in both groups had similar demographics, cardiovascular risk factors, and extent of disease. In the primary intervention group (mean follow-up, 29 ± 12 months), patients treated by CS had higher freedom from restenosis (92% ± 6% vs 53% ± 4%; P =.003), symptom recurrence (92 ± 4% vs 50 ± 5%; P =.003), reintervention (91% ± 6% vs 56% ± 5%; P =.005), and better primary patency at 3 years (92% ± 6% vs 52% ± 5%; P <.003) than for BMS. In the reintervention group (mean follow-up, 24 ± 9 months), patients treated by CS had higher freedom from restenosis (89% ± 10% vs 49% ± 14%; P <.04), symptom recurrence (100% vs 64%± 9%; P =.001), and reintervention (100% vs 72% ± 9%; P =.03) at 1 year, and a trend toward improved primary patency at 1 year (100% vs 63% ± 9%; P =.054). Secondary patency rates were similar in both groups. Conclusions: In this nonrandomized study, CS were associated with less restenosis, recurrences, and reinterventions than BMS in patients undergoing primary interventions or reinterventions for CMI.
AB - Objective: To compare outcomes of mesenteric angioplasty and stenting using iCAST covered stents (CS; Atrium, Hudson, NH) or bare metal stents (BMS) in patients with chronic mesenteric ischemia (CMI). Methods: We reviewed the clinical data of 225 patients (65 male and 160 female; mean age, 72 ± 12 years) treated for CMI at two academic centers (2000-2010). Outcomes were analyzed in patients who had primary intervention or reintervention using BMS (n = 164 patients/197 vessels) or CS (n = 61 patients/67 vessels). End points were freedom from restenosis, symptom recurrence, reinterventions, and patency rates. Results: Patients in both groups had similar demographics, cardiovascular risk factors, and extent of disease. In the primary intervention group (mean follow-up, 29 ± 12 months), patients treated by CS had higher freedom from restenosis (92% ± 6% vs 53% ± 4%; P =.003), symptom recurrence (92 ± 4% vs 50 ± 5%; P =.003), reintervention (91% ± 6% vs 56% ± 5%; P =.005), and better primary patency at 3 years (92% ± 6% vs 52% ± 5%; P <.003) than for BMS. In the reintervention group (mean follow-up, 24 ± 9 months), patients treated by CS had higher freedom from restenosis (89% ± 10% vs 49% ± 14%; P <.04), symptom recurrence (100% vs 64%± 9%; P =.001), and reintervention (100% vs 72% ± 9%; P =.03) at 1 year, and a trend toward improved primary patency at 1 year (100% vs 63% ± 9%; P =.054). Secondary patency rates were similar in both groups. Conclusions: In this nonrandomized study, CS were associated with less restenosis, recurrences, and reinterventions than BMS in patients undergoing primary interventions or reinterventions for CMI.
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U2 - 10.1016/j.jvs.2013.05.013
DO - 10.1016/j.jvs.2013.05.013
M3 - Article
C2 - 23827340
AN - SCOPUS:84886598232
SN - 0741-5214
VL - 58
SP - 1316
EP - 1324
JO - Journal of vascular surgery
JF - Journal of vascular surgery
IS - 5
ER -