Comparison of 64-slice computed tomography planimetry and Doppler echocardiography in the assessment of aortic valve stenosis

Michel Habis, Beatrice Daoud, Veronique L. Roger, Said Ghostine, Christophe Caussin, Ramzi Ramadan, Remi Nottin, Bernard Lancelin, Claude Yves Angel, Andre Capderou, Jean Francois Paul

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Background and aim of the study: The study aim was to compare, prospectively, the planimetry of aortic stenosis on 64-slice computed tomography (CT), with the area calculated by Doppler transthoracic echocardiography (TTE) in symptomatic patients evaluated before potential aortic valve replacement. Methods: Fifty-two consecutive patients (27 males, 25 females; mean age 74 ± 10 years) admitted to the authors' institution during 2005 were evaluated with 64-slice CT and Doppler TTE. The time interval between the two evaluations was 2 ± 1 weeks. Planimetry of the anatomic orifice area (AOA) drawn on 64-slice CT was compared to the effective area determined by Doppler TTE by Bland and Altman analysis, and the anatomic area threshold value corresponding to a significant effective aortic stenosis (≤0.75 cm2) was determined by receiver operating characteristic (ROC) analysis. Results: The aortic orifice area measured by 64-slice CT correlated well with the effective area (r = 0.76; p <0.0001), but was significantly greater, with a systematic overestimation (0.132 cm2) and a variability of 0.239 cm2. There was good agreement between planimetry determined by two independent radiologists (difference = 0.002, variability = 0.115 cm2). ROC analysis showed that a threshold value of 0.95 cm2 as measured by 64-slice CT planimetry identifies significant aortic stenosis with sensitivity, specificity, accuracy, positive and negative predictive values of 82%, 77%, 81%, 91% and 59%, respectively. Conclusion: 64-slice CT is a reproducible and reliable non-invasive method to evaluate aortic valve stenosis compared to the reference method of Doppler TTE. Indeed, the CT approach could replace the latter evaluation when measurements used in the continuity equation are inadequate.

Original languageEnglish (US)
Pages (from-to)216-224
Number of pages9
JournalJournal of Heart Valve Disease
Issue number3
StatePublished - May 1 2007

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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