Comb-Push Ultrasound Shear Elastography of thyroid: Preliminary in vivo human study

Mohammad Mehrmohammadi, Max Denis, Pengfei Song, Shigao Chen, Mostafa Fatemi, Azra Alizad

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations


Shear wave elastography (SWE) techniques have been introduced and have shown promising potency in providing diagnostic information about thyroid nodules. Comb-push Ultrasound Shear Elastography (CUSE) has been recently introduced as a technique that is capable of measuring mechanical properties of soft tissues with a novel acoustic radiation force excitation fashion, leading to notable advantages of fast acquisition of shear wave speed data within a large field of view. In this study, we demonstrated the preliminary utility of CUSE in imaging thyroid tissue and thyroid nodules in a group of 5 healthy volunteers and 10 patients. The shear wave speed values were converted into Young's modulus (E) and suggested a clear difference between benign (91.2±34.8 kPa) and malignant (173.0±17.1 kPa) thyroid nodules, thus indicating the potential of using CUSE in differentiating between benign and malignant nodules in thyroid.

Original languageEnglish (US)
Title of host publicationIEEE International Ultrasonics Symposium, IUS
PublisherIEEE Computer Society
Number of pages4
ISBN (Electronic)9781479970490
StatePublished - Oct 20 2014
Event2014 IEEE International Ultrasonics Symposium, IUS 2014 - Chicago, United States
Duration: Sep 3 2014Sep 6 2014

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727


Other2014 IEEE International Ultrasonics Symposium, IUS 2014
Country/TerritoryUnited States


  • In vivo
  • Shear Wave
  • Thyroid Cancer
  • Tissue Elasticity
  • Ultrasound

ASJC Scopus subject areas

  • Acoustics and Ultrasonics


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