Clip and dip: Fatal forty DDI: Carbamazepine, felodipine, CYP3A4

David W. Barbara, Randall Flick, Juraj Sprung

Research output: Chapter in Book/Report/Conference proceedingChapter


This case discusses the pharmacokinetic interaction between felodipine, carbamzapine, and phenytoin, resulting in decreased antihypertensive effi cacy. Felodipine is a cytochrome P450 3A4 substrate and carbamzepine and phenytoin are 3A4 inducers.

Original languageEnglish (US)
Title of host publicationA Case Approach to Perioperative Drug-Drug Interactions
PublisherSpringer New York
Number of pages4
ISBN (Electronic)9781461474951
ISBN (Print)9781461474944
StatePublished - Sep 15 2015

ASJC Scopus subject areas

  • General Medicine


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