Clinical trials in brain tumor surgery

Jason M. Hoover, Susan M. Chang, Ian F. Parney

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


The prognosis for patients diagnosed with primary central nervous system tumors, such as gliomas, remains generally poor. Improved treatment (standard therapies and novel strategies) is needed. Glioma surgery is a key part of standard treatment and has established roles in providing tissue for diagnosis and in tumor debulking. Several techniques to increase safe surgical resection have been investigated. In addition, novel surgical modalities introducing therapeutic agents locally are increasingly common. This article reviews recent glioma surgery clinical trials, focusing on outcome studies, novel surgical techniques, and local therapeutic agent delivery.

Original languageEnglish (US)
Pages (from-to)409-424
Number of pages16
JournalNeuroimaging Clinics of North America
Issue number3
StatePublished - Aug 2010


  • Brain tumor
  • Central nervous system
  • Cytoreductive surgery
  • Gliomas

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology


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