Clinical spectrum of neuropathy after primary total knee arthroplasty: A series of 54 cases

Scott J.A. Speelziek, Nathan P. Staff, Rebecca L. Johnson, Rafael J. Sierra, Ruple S. Laughlin

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Introduction: Neuropathy after total knee arthroplasty (TKA) can cause significant morbidity but is inconsistently reported. Methods: We reviewed the clinical, electrodiagnostic and perioperative features of all patients who underwent primary TKA at our institution and developed a new neuropathy within 8 weeks postoperatively. Results: Fifty-four cases were identified (incidence 0.37% [95% confidence interval, 0.28–0.49]) affecting the following nerve(s): peroneal (37), sciatic (11), ulnar (2), tibial (2), sural (1), and lumbosacral plexus (1). In all cases with follow-up data, motor recovery typically occurred within 1 year and was complete or near-complete. Conclusions: Post-TKA neuropathy is uncommon, typically does not require intervention and usually resolves within 1 year. Post-TKA neuropathy most often affects the nerves surgically at risk. Anesthesia type does not correlate with post-TKA neuropathy. An inflammatory etiology for post-TKA neuropathy is rare but should be considered in specific cases. Muscle Nerve 59:679–682, 2019.

Original languageEnglish (US)
Pages (from-to)679-682
Number of pages4
JournalMuscle and Nerve
Issue number6
StatePublished - Jun 2019


  • electromyography
  • iatrogenic
  • neuropathy
  • postoperative
  • sciatic

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)


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