Clinical features of multiple glomus tumors

Okechukwu A. Anakwenze, Wendy L. Parker, Terry K. Schiefer, Carrie Y. Inwards, Robert J. Spinner, Peter C. Amadio

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


BACKGROUND While glomus tumors are usually solitary, multiple glomus tumors do occur. The purpose of this study was to review the clinical characteristics and outcomes in a series of patients with multiple glomus tumors presenting to our institution. METHODS A retrospective review of patients with multiple glomus tumors seen at our institution over the past 25years was performed. RESULTS Twenty-two patients with multiple glomus tumors were identified. Initial diagnosis was blue rubber nevus syndrome and hemangioma in 10 and 7 patients, respectively. The mean duration from onset of symptoms until correct diagnosis was 14.6years. Involvement of an extremity was noted in 90.9% of the patients. An autosomal dominant pattern of inheritance was noted in 13 of 22 patients. The classic triad of symptoms in solitary glomus tumors-pain, pinpoint tenderness, and cold hypersensitivity-was noted in only 1 of the 22 patients; pain and pinpoint tenderness were simultaneously identified in 14 patients, 8 with visible lesions but no symptoms. Symptoms were relieved by surgical excision in most patients. CONCLUSION Patients with multiple glomus tumors are frequently misdiagnosed. Proper recognition and diagnosis would lead to improved management.

Original languageEnglish (US)
Pages (from-to)884-890
Number of pages7
JournalDermatologic Surgery
Issue number7
StatePublished - Jul 2008

ASJC Scopus subject areas

  • Surgery
  • Dermatology


Dive into the research topics of 'Clinical features of multiple glomus tumors'. Together they form a unique fingerprint.

Cite this