Circulating insulin-like growth factor system adaptations in hibernating brown bears indicate increased tissue IGF availability

Medicine & Life Sciences

• Hibernation 100%
• Somatomedins 93%
• Insulin-Like Growth Factor Binding Proteins 51%
• Insulin-Like Growth Factor Binding Protein 2 41%
• Ursidae 29%
• Insulin-Like Growth Factor Binding Protein 3 24%
• Acids 22%
• insulin-like growth factor binding protein, acid labile subunit 18%
• Tissue Preservation 13%
• RNA Isoforms 13%
• Bone and Bones 11%
• RNA Sequence Analysis 10%
• Liver 10%
• Gel Chromatography 9%
• Heparin 8%
• Molecular Weight 8%
• Ligands 6%
• Western Blotting 6%
• Muscles 5%
• Messenger RNA 5%
• Therapeutics 1%