Chemoprevention of breast cancer

Julia A. Files, Daniela L. Stan, Summer V. Allen, Sandhya Pruthi

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


The development of pharmacologic agents for the prevention of breast cancer is a significant milestone in medical and laboratory research. Despite these advances, the endorsement of preventive options has become challenging and complex, as physicians are expected to counsel and tailor their recommendations using a personalized approach taking into account medical comorbidities, degree of risk and patient preferences. This article provides a comprehensive overview of the major breast cancer prevention trials, review of the pharmacologic options available for breast cancer prevention, and strategies for integrating chemoprevention of breast cancer in high-risk women into clinical practice.

Original languageEnglish (US)
Pages (from-to)635-646
Number of pages12
JournalWomen's Health
Issue number6
StatePublished - Nov 2012


  • Gail Model
  • aromatase inhibitor
  • breast cancer prevention
  • breast cancer risk
  • chemoprevention
  • high-risk women
  • raloxifene
  • tamoxifen

ASJC Scopus subject areas

  • General Medicine


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