Chemoprevention in Barrett's oesophagus

Anushka Baruah; Navtej S. Buttar

doi:10.1016/j.bpg.2014.12.003

Chemoprevention in Barrett's oesophagus

Anushka Baruah, Navtej S. Buttar

Gastroenterology and Hepatology

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

Increasing incidence of oesophageal adenocarcinoma along with poor survival entails novel preventive strategies. Agents that target pro-oncogenic pathways in Barrett's mucosa could halt this neoplastic transformation. In this review, we will use epidemiological associations and molecular mechanisms to identify novel chemoprevention targets in Barrett's oesophagus. We will also discuss recent chemoprevention trials.

Original language	English (US)
Pages (from-to)	151-165
Number of pages	15
Journal	Best Practice and Research: Clinical Gastroenterology
Volume	29
Issue number	1
DOIs	https://doi.org/10.1016/j.bpg.2014.12.003
State	Published - Feb 1 2015

Keywords

Barrett's oesophagus(BO)
Chemo-preventive agents
Oesophageal adenocarcinoma(OAC)
Surrogate endpoint markers(SEBs)

ASJC Scopus subject areas

Gastroenterology

Access to Document

10.1016/j.bpg.2014.12.003

Cite this

@article{b9e1c720760a4cf68a0f662dbd3edbef,

title = "Chemoprevention in Barrett's oesophagus",

abstract = "Increasing incidence of oesophageal adenocarcinoma along with poor survival entails novel preventive strategies. Agents that target pro-oncogenic pathways in Barrett's mucosa could halt this neoplastic transformation. In this review, we will use epidemiological associations and molecular mechanisms to identify novel chemoprevention targets in Barrett's oesophagus. We will also discuss recent chemoprevention trials.",

keywords = "Barrett's oesophagus(BO), Chemo-preventive agents, Oesophageal adenocarcinoma(OAC), Surrogate endpoint markers(SEBs)",

author = "Anushka Baruah and Buttar, {Navtej S.}",

note = "Publisher Copyright: {\textcopyright} 2014 Published by Elsevier Ltd.",

year = "2015",

month = feb,

day = "1",

doi = "10.1016/j.bpg.2014.12.003",

language = "English (US)",

volume = "29",

pages = "151--165",

journal = "Best Practice and Research: Clinical Gastroenterology",

issn = "1521-6918",

publisher = "Bailliere Tindall Ltd",

number = "1",

}

TY - JOUR

T1 - Chemoprevention in Barrett's oesophagus

AU - Baruah, Anushka

AU - Buttar, Navtej S.

PY - 2015/2/1

Y1 - 2015/2/1

N2 - Increasing incidence of oesophageal adenocarcinoma along with poor survival entails novel preventive strategies. Agents that target pro-oncogenic pathways in Barrett's mucosa could halt this neoplastic transformation. In this review, we will use epidemiological associations and molecular mechanisms to identify novel chemoprevention targets in Barrett's oesophagus. We will also discuss recent chemoprevention trials.

AB - Increasing incidence of oesophageal adenocarcinoma along with poor survival entails novel preventive strategies. Agents that target pro-oncogenic pathways in Barrett's mucosa could halt this neoplastic transformation. In this review, we will use epidemiological associations and molecular mechanisms to identify novel chemoprevention targets in Barrett's oesophagus. We will also discuss recent chemoprevention trials.

KW - Barrett's oesophagus(BO)

KW - Chemo-preventive agents

KW - Oesophageal adenocarcinoma(OAC)

KW - Surrogate endpoint markers(SEBs)

UR - http://www.scopus.com/inward/record.url?scp=84925095928&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84925095928&partnerID=8YFLogxK

U2 - 10.1016/j.bpg.2014.12.003

DO - 10.1016/j.bpg.2014.12.003

M3 - Review article

C2 - 25743463

AN - SCOPUS:84925095928

SN - 1521-6918

VL - 29

SP - 151

EP - 165

JO - Best Practice and Research: Clinical Gastroenterology

JF - Best Practice and Research: Clinical Gastroenterology

IS - 1

ER -

Chemoprevention in Barrett's oesophagus

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this