Changing transfusion practices in hip and knee arthroplasty

D. O. Warner, M. A. Warner, D. R. Schroeder, K. P. Offord, P. Maxson, P. Santrach

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


BACKGROUND: This study was designed to examine changes in perioperative transfusion practices after the introduction of autologous blood conservation strategies into routine clinical practice. STUDY DESIGN AND METHODS: The existing medical records of all patients undergoing total hip or knee arthroplasty at Mayo Clinic in Rochester, MN, who resided in Olmsted County, were reviewed over three periods: 1981-82 (232 procedures), 1987-88 (269 procedures), and 1993-94 (398 procedures). RESULTS: The proportion of patients receiving any perioperative red cell (RBC) units significantly decreased (from 85% in 1981-82 to 65% in 1993-94). The timing of transfusion also changed; the proportion of RBC units transfused in the preoperative or intraoperative periods decreased from 68 percent in 1981-82 to 38 percent in 1993-94, with the balance of RBC units transfused in the postoperative period. Although the number of RBC units utilized per procedure in the intraoperative period significantly decreased, the number of RBC units transfused in the postoperative period significantly increased (from 0.6 ± 1.0 to 1.1 ± 1.4 units per procedure in 1981-82 and 1993-94, respectively, p<0.05). CONCLUSION: Although blood conservation strategies have been successful in reducing RBC transfusion intraoperatively, avoidance of intraoperative transfusion may in some cases postpone, rather than prevent, transfusion.

Original languageEnglish (US)
Pages (from-to)738-744
Number of pages7
Issue number8
StatePublished - Aug 1998

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Hematology


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