TY - JOUR
T1 - Cerebrospinal Fluid Physiology and the Management of Increased Intracranial Pressure
AU - LYONS, MARK K.
AU - MEYER, FREDRIC B.
PY - 1990
Y1 - 1990
N2 - Increased intracranial pressure can result in irreversible injury to the central nervous system. Among the many functions of the cerebrospinal fluid, it provides protection against acute changes in venous and arterial blood pressure or impact pressure. Nevertheless, trauma, tumors, infections, neurosurgical procedures, and other factors can cause increased intracranial pressure. Both surgical and nonsurgical therapeutic modalities can be used in the management of increased intracranial pressure attributable to traumatic and nontraumatic causes. In patients with cerebral injury and increased intracranial pressure, monitoring of the intracranial pressure can provide an objective measure of the response to therapy and the pressure dynamics. Intraventricular, intraparenchymal, subarachnoid, and epidural sites can be used for monitoring, and the advantages and disadvantages of the various devices available are discussed. With the proper understanding of the physiologic features of the cerebrospinal fluid, the physician can apply the management principles reviewed herein to minimize damage from intracranial hypertension.
AB - Increased intracranial pressure can result in irreversible injury to the central nervous system. Among the many functions of the cerebrospinal fluid, it provides protection against acute changes in venous and arterial blood pressure or impact pressure. Nevertheless, trauma, tumors, infections, neurosurgical procedures, and other factors can cause increased intracranial pressure. Both surgical and nonsurgical therapeutic modalities can be used in the management of increased intracranial pressure attributable to traumatic and nontraumatic causes. In patients with cerebral injury and increased intracranial pressure, monitoring of the intracranial pressure can provide an objective measure of the response to therapy and the pressure dynamics. Intraventricular, intraparenchymal, subarachnoid, and epidural sites can be used for monitoring, and the advantages and disadvantages of the various devices available are discussed. With the proper understanding of the physiologic features of the cerebrospinal fluid, the physician can apply the management principles reviewed herein to minimize damage from intracranial hypertension.
UR - http://www.scopus.com/inward/record.url?scp=0025332741&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025332741&partnerID=8YFLogxK
U2 - 10.1016/S0025-6196(12)65131-3
DO - 10.1016/S0025-6196(12)65131-3
M3 - Review article
C2 - 2190050
AN - SCOPUS:0025332741
SN - 0025-6196
VL - 65
SP - 684
EP - 707
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 5
ER -