TY - JOUR
T1 - Cerebellar ataxia from multiple potential causes
T2 - Hypothyroidism, hashimoto’s thyroiditis, thalamic stimulation, and essential tremor
AU - Shneyder, Natalya
AU - Lyons, Mark K.
AU - Driver-Dunckley, Erika
AU - Evidente, Virgilio Gerald H.
N1 - Funding Information:
* To whom correspondence should be addressed. E-mail: Evidente.Virgilio@mayo.edu Editor: Elan D. Louis, Columbia UniversityUnited States of America Received: June 14, 2011 Accepted: October 26, 2011 Published: March 22, 2012 Copyright: ’ 2012 Shneyder et al. This is an open-access article distributed under the terms of the Creative Commons Attribution–Noncommercial–No Derivatives License, which permits the user to copy, distribute, and transmit the work provided that the original author(s) and source are credited; that no commercial use is made of the work; and that the work is not altered or transformed. Funding: Erika Driver-Dunckley received research funding from Ipsen, Chelsea, Merck Serono, and UCB-Schwarz. Virgilio Gerald H. Evidente received research funding from Allergan, UCB-Schwarz, Merz, Ipsen, and Allon. Competing Interests: Virgilio Gerald H. Evidente MD reports consulting and/or advisory board activities for Merz, Teva, Ipsen, and GSK.
Publisher Copyright:
© 2012 Shneyder et al.
PY - 2012
Y1 - 2012
N2 - Background: Both hypothyroidism and Hashimoto’s thyroiditis (HT) can rarely be associated with cerebellar ataxia. Severe essential tremor (ET) as well as bilateral thalamic deep brain stimulation (DBS) may lead to subtle cerebellar signs. Case Report: We report a 74-year-old male with hypothyroidism and a 20-year history of ET who developed cerebellar ataxia after bilateral thalamic DBS. Extensive workup revealed elevated thyroid stimulating hormone and thyroperoxidase antibody titers confirming the diagnosis of HT. Discussion: Our case demonstrates multiple possible causes of cerebellar ataxia in a patient, including hypothyroidism, HT, chronic ET, and bilateral thalamic DBS. Counseling of patients may be appropriate when multiple risk factors for cerebellar ataxia coexist in one individual.
AB - Background: Both hypothyroidism and Hashimoto’s thyroiditis (HT) can rarely be associated with cerebellar ataxia. Severe essential tremor (ET) as well as bilateral thalamic deep brain stimulation (DBS) may lead to subtle cerebellar signs. Case Report: We report a 74-year-old male with hypothyroidism and a 20-year history of ET who developed cerebellar ataxia after bilateral thalamic DBS. Extensive workup revealed elevated thyroid stimulating hormone and thyroperoxidase antibody titers confirming the diagnosis of HT. Discussion: Our case demonstrates multiple possible causes of cerebellar ataxia in a patient, including hypothyroidism, HT, chronic ET, and bilateral thalamic DBS. Counseling of patients may be appropriate when multiple risk factors for cerebellar ataxia coexist in one individual.
KW - Ataxia
KW - Deep brain stimulation
KW - Hashimoto’s thyroiditis
KW - Hypothyroidism
KW - Thalamic stimulation
KW - Tremor
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U2 - 10.5334/TOHM.100
DO - 10.5334/TOHM.100
M3 - Article
AN - SCOPUS:85048085845
SN - 2160-8288
VL - 2
JO - Tremor and Other Hyperkinetic Movements
JF - Tremor and Other Hyperkinetic Movements
ER -