Centrosomes: Sfi1p and Centrin Unravel a Structural Riddle

Research output: Contribution to journalReview articlepeer-review

56 Scopus citations


The discovery of Sfi1p as a novel binding partner for the Ca 2+-binding protein centrin has provided new insight into the dynamic behavior of centrosomes. Sfi1 binds to multiple centrin molecules along a series of internal repeats, and the complex forms Ca2+-sensitive contractile fibers that function to reorient centrioles and alter centrosome structure.

Original languageEnglish (US)
Pages (from-to)R27-R29
JournalCurrent Biology
Issue number1
StatePublished - Jan 6 2004

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences


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