Centrilobular opacities in the lung on high-resolution CT: Diagnostic considerations and pathologic correlation

Accurate assessment of high-resolution CT scans of the lung requires a knowledge of secondary lobular anatomy. Opacity that localizes to the centrilobular implies the presence of a disease process that primarily involves centrilobular bronchioles, lymphatics, or pulmonary arterial branches. We illustrate the high-resolution CT findings of many of these processes and provide pathologic correlation for cases in which it was available.