Central nervous system tumors

Ravi D. Rao, Paul D. Brown, Caterina Giannini, Cormac O. Maher, Fredric B. Meyer, Evanthia Galanis, Brad J. Erickson, Jan C. Buckner

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


The term primary central nervous system tumors refers to a heterogeneous group of tumors characterized by their location in the central nervous system (CNS). These tumors exhibit a wide range of clinical behavior from extremely lethal (e.g., glioblastoma) to potentially curable (e.g., germ cell tumors and medulloblastomas). The occurrence of these tumors has devastating effects on patients, and their management can be major challenge to physicians. By virtue of their location, brain tumors cause a disproportionate amount of disability and pose a threat to a patient's sense of self that is unparalleled by any other disease. The currently available therapies for most primary CNS tumors have limited activity with significant toxicity. Survivors of these tumors often have significant residual neurologic and cognitive deficits that limit their functioning for the rest of their lives.

Original languageEnglish (US)
Title of host publicationOncology
Subtitle of host publicationAn Evidence-Based Approach
PublisherSpringer New York
Number of pages19
ISBN (Print)0387242910, 9780387242910
StatePublished - Dec 1 2006

ASJC Scopus subject areas

  • Medicine(all)


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