Central hyperadrenergic state after lightning strike

Ajay K. Parsaik; J. Eric Ahlskog; Wolfgang Singer; Russell Gelfman; Seth H. Sheldon; Richard J. Seime; Jennifer M. Craft; Jeffrey P. Staab; Birgit Kantor; Phillip A. Low

doi:10.1007/s10286-013-0197-7

Central hyperadrenergic state after lightning strike

Ajay K. Parsaik, J. Eric Ahlskog, Wolfgang Singer, Russell Gelfman, Seth H. Sheldon, Richard J. Seime, Jennifer M. Craft, Jeffrey P. Staab, Birgit Kantor, Phillip A. Low

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Objective: To describe and review autonomic complications of lightning strike. Methods: Case report and laboratory data including autonomic function tests in a subject who was struck by lightning. Results: A 24-year-old man was struck by lightning. Following that, he developed dysautonomia, with persistent inappropriate sinus tachycardia and autonomic storms, as well as posttraumatic stress disorder (PTSD) and functional neurologic problems. Interpretation: The combination of persistent sinus tachycardia and episodic exacerbations associated with hypertension, diaphoresis, and agitation was highly suggestive of a central hyperadrenergic state with superimposed autonomic storms. Whether the additional PTSD and functional neurologic deficits were due to a direct effect of the lightning strike on the central nervous system or a secondary response is open to speculation.

Original language	English (US)
Pages (from-to)	169-173
Number of pages	5
Journal	Clinical Autonomic Research
Volume	23
Issue number	4
DOIs	https://doi.org/10.1007/s10286-013-0197-7
State	Published - Aug 2013

Keywords

Hyperadrenergic
Neuropathy
PTSD
Tachycardia

ASJC Scopus subject areas

Endocrine and Autonomic Systems
Clinical Neurology

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10.1007/s10286-013-0197-7

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title = "Central hyperadrenergic state after lightning strike",

abstract = "Objective: To describe and review autonomic complications of lightning strike. Methods: Case report and laboratory data including autonomic function tests in a subject who was struck by lightning. Results: A 24-year-old man was struck by lightning. Following that, he developed dysautonomia, with persistent inappropriate sinus tachycardia and autonomic storms, as well as posttraumatic stress disorder (PTSD) and functional neurologic problems. Interpretation: The combination of persistent sinus tachycardia and episodic exacerbations associated with hypertension, diaphoresis, and agitation was highly suggestive of a central hyperadrenergic state with superimposed autonomic storms. Whether the additional PTSD and functional neurologic deficits were due to a direct effect of the lightning strike on the central nervous system or a secondary response is open to speculation.",

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note = "Funding Information: Acknowledgments This work was supported in part by National Institutes of Health (NS 44233 Pathogenesis and Diagnosis of Multiple System Atrophy, U54 NS065736 Autonomic Rare Disease Clinical Consortium), Mayo CTSA (UL1 TR000135), and Mayo Funds. The Autonomic Diseases Consortium is a part of the NIH Rare Diseases Clinical Research Network (RDCRN). Funding and/or programmatic support for this project has been provided by U54 NS065736 from the National Institute of Neurological Diseases and Stroke (NINDS) and the NIH Office of Rare Diseases Research (ORDR). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National",

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AU - Parsaik, Ajay K.

AU - Ahlskog, J. Eric

AU - Singer, Wolfgang

AU - Gelfman, Russell

AU - Sheldon, Seth H.

AU - Seime, Richard J.

AU - Craft, Jennifer M.

AU - Staab, Jeffrey P.

AU - Kantor, Birgit

AU - Low, Phillip A.

N1 - Funding Information: Acknowledgments This work was supported in part by National Institutes of Health (NS 44233 Pathogenesis and Diagnosis of Multiple System Atrophy, U54 NS065736 Autonomic Rare Disease Clinical Consortium), Mayo CTSA (UL1 TR000135), and Mayo Funds. The Autonomic Diseases Consortium is a part of the NIH Rare Diseases Clinical Research Network (RDCRN). Funding and/or programmatic support for this project has been provided by U54 NS065736 from the National Institute of Neurological Diseases and Stroke (NINDS) and the NIH Office of Rare Diseases Research (ORDR). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National

PY - 2013/8

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N2 - Objective: To describe and review autonomic complications of lightning strike. Methods: Case report and laboratory data including autonomic function tests in a subject who was struck by lightning. Results: A 24-year-old man was struck by lightning. Following that, he developed dysautonomia, with persistent inappropriate sinus tachycardia and autonomic storms, as well as posttraumatic stress disorder (PTSD) and functional neurologic problems. Interpretation: The combination of persistent sinus tachycardia and episodic exacerbations associated with hypertension, diaphoresis, and agitation was highly suggestive of a central hyperadrenergic state with superimposed autonomic storms. Whether the additional PTSD and functional neurologic deficits were due to a direct effect of the lightning strike on the central nervous system or a secondary response is open to speculation.

AB - Objective: To describe and review autonomic complications of lightning strike. Methods: Case report and laboratory data including autonomic function tests in a subject who was struck by lightning. Results: A 24-year-old man was struck by lightning. Following that, he developed dysautonomia, with persistent inappropriate sinus tachycardia and autonomic storms, as well as posttraumatic stress disorder (PTSD) and functional neurologic problems. Interpretation: The combination of persistent sinus tachycardia and episodic exacerbations associated with hypertension, diaphoresis, and agitation was highly suggestive of a central hyperadrenergic state with superimposed autonomic storms. Whether the additional PTSD and functional neurologic deficits were due to a direct effect of the lightning strike on the central nervous system or a secondary response is open to speculation.

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Central hyperadrenergic state after lightning strike

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Keywords

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