Cell-mediated therapies to facilitate operational tolerance in liver transplantation

Samia D. Ellias, Ellen L. Larson, Timucin Taner, Scott L. Nyberg

Research output: Contribution to journalArticlepeer-review


Cell therapies using immune cells or non-parenchymal cells of the liver have emerged as potential treatments to facilitate immunosuppression withdrawal and to induce operational tolerance in liver transplant (LT) recipients. Recent pre-clinical and clinical trials of cellular therapies including regulatory T cells, regulatory dendritic cells, and mesenchymal cells have shown promising results. Here we briefly summarize current concepts of cellular therapy for induction of operational tolerance in LT recipients.

Original languageEnglish (US)
Article number4016
JournalInternational journal of molecular sciences
Issue number8
StatePublished - Apr 2 2021


  • Dendritic cells
  • Liver transplantation
  • Mesenchymal cells
  • Operational tolerance
  • Regulatory T cells
  • Transplant immunology

ASJC Scopus subject areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


Dive into the research topics of 'Cell-mediated therapies to facilitate operational tolerance in liver transplantation'. Together they form a unique fingerprint.

Cite this