Catheter ablation for atrial fibrillation in patients with the Marfan and Marfan-like syndromes

T. Jared Bunch, Heidi M. Connolly, Samuel J. Asirvatham, Peter A. Brady, Bernard J. Gersh, Thomas M. Munger, Win Kuang Shen, Kristi H. Monahan, Douglas L. Packer

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Patients with the Marfan syndrome may pose a difficult challenge for catheter-based interventions due to frequent coexisting valve disease, potential delay in vascular healing and repair, and intra-atrial scar from prior cardiac surgery. We report a case series of four patients with Marfan or Marfan-like syndromes who underwent ablation for drug-refractory atrial fibrillation. Ultimately three of four patients remained in sinus rhythm, however most patients required multiple ablative attempts and long-term atrial flutter was common. Nonetheless, peri-procedural complications were minimal despite the connective tissue disorder and prosthetic valves in three of four patients. In conclusion, catheter ablation of AF in patients with Marfan syndrome is a viable option in those individuals refractory to conventional therapy.

Original languageEnglish (US)
Pages (from-to)15-20
Number of pages6
JournalJournal of Interventional Cardiac Electrophysiology
Issue number1-2
StatePublished - Nov 2007


  • Ablation, Aortic aneurysm
  • Atrial fibrillation
  • Marfan syndrome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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