TY - JOUR
T1 - Catecholamines
AU - Axelrod, Julius
AU - Weinshilboum, Richard
PY - 1972/8/3
Y1 - 1972/8/3
N2 - THE catecholamines — dopamine, adrenaline (epinephrine) and noradrenaline (norepinephrine) — are found at specific locations in tissues. Noradrenaline is present mainly in the sympathetic nerves of the peripheral and central nervous systems and acts locally on effector cells of vascular smooth muscle, adipose tissue, liver, heart and brain as a neurotransmitter. Adrenaline is primarily located in the adrenal medulla and acts mainly as a hormone on distant target organs after its release from the adrenal gland into the bloodstream. Dopamine has two functions: it serves as a precursor of noradrenaline, and it presumably functions as a neurotransmitter in the areas.
AB - THE catecholamines — dopamine, adrenaline (epinephrine) and noradrenaline (norepinephrine) — are found at specific locations in tissues. Noradrenaline is present mainly in the sympathetic nerves of the peripheral and central nervous systems and acts locally on effector cells of vascular smooth muscle, adipose tissue, liver, heart and brain as a neurotransmitter. Adrenaline is primarily located in the adrenal medulla and acts mainly as a hormone on distant target organs after its release from the adrenal gland into the bloodstream. Dopamine has two functions: it serves as a precursor of noradrenaline, and it presumably functions as a neurotransmitter in the areas.
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U2 - 10.1056/NEJM197208032870508
DO - 10.1056/NEJM197208032870508
M3 - Review article
C2 - 4402575
AN - SCOPUS:0015493132
SN - 0028-4793
VL - 287
SP - 237
EP - 242
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 5
ER -