Carotid imaging

W. Brinjikji, G. Lanzino, J. M. Morris, A. A. Rabinstein, H. J. Cloft

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Stroke is the second most common cause of death in developed countries and carotid atherosclerotic disease accounts for up to 25% of strokes. A high degree of stenosis, inflammation of the plaque, thin fibrous caps, intraplaque hemorrhage and lipid rich necrotic cores are strongly predictive of future embolic events in patients with carotid stenosis. Thus, the ability to detect these pathologies in patients with stenosis is essential to preventing future embolic events. Over the past decade, great advances have been made in carotid imaging as we cannot only effectively measure degree of stenosis of carotid arteries, but also measure prognostic variables such as degree of inflammation, macrophage infiltration, fibrous cap to lipid-rich core ratio and intraplaque hemorrhage with improved imaging techniques and technologies. The purpose of this review was to inform the surgical community on the advancements that have been made in carotid imaging specifically focusing on techniques that allow clinicians to distinguish between dangerous and innocuous plaques.

Original languageEnglish (US)
Pages (from-to)249-258
Number of pages10
JournalItalian Journal of Vascular and Endovascular Surgery
Volume16
Issue number4
StatePublished - Dec 2009

Keywords

  • Carotid artery diseases
  • Carotid stenosis
  • Diagnostic imaging
  • Stroke

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

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