Cardiovascular consequences of obstructive sleep apnea

Robert Wolk, Virend K. Somers

Research output: Contribution to journalReview articlepeer-review

48 Scopus citations


Sleep apnea is associated with several cardiovascular disease conditions. A causal relationship between sleep apnea and each of these diseases is likely, but remains to be proven. The clearest evidence implicating OSA in the development of new cardiovascular disease involves data that show an increased prevalence of new hypertension in patients with OSA followed over 4 years [3]. Circumstantial evidence and data from small study samples suggest that OSA, in the setting of existing cardiovascular disease, may exacerbate symptoms and accelerate disease progression. The diagnosis of OSA always should be considered in patients with refractory heart failure, resistant hypertension, nocturnal cardiac ischemia, and nocturnal arrhythmias, especially in individuals with risk factors for sleep apnea (eg, central obesity, age, and male gender). Treating sleep apnea may help to achieve better clinical control in these diseases and may improve long-term cardiovascular prognosis.

Original languageEnglish (US)
Pages (from-to)195-205
Number of pages11
JournalClinics in Chest Medicine
Issue number2
StatePublished - Jun 2003

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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