Cardiorenal syndrome in decompensated heart failure: prognostic and therapeutic implications.

Guido Boerrigter, John C. Burnett

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


Various lines of evidence implicate impaired renal function as an important prognostic indicator in patients with congestive heart failure (CHF). Conventional diuretics may aggravate renal dysfunction and can result in neurohumoral activation. Evolving new therapeutic strategies that enhance renal function include administration of B-type natriuretic peptide, adenosine and vasopressin antagonists, and ultrafiltration methods. Prospective studies are needed to evaluate whether these new renal-enhancing strategies will improve patient outcome in CHF.

Original languageEnglish (US)
Pages (from-to)113-120
Number of pages8
JournalCurrent heart failure reports
Issue number3
StatePublished - 2004

ASJC Scopus subject areas

  • Emergency Medicine
  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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