Cardiac sympathetic activity in stress-induced (Takotsubo) cardiomyopathy

Abhiram Prasad, Malini Madhavan, Panithaya Chareonthaitawee

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


Background. A 54-year-old postmenopausal woman presented with retrosternal chest pressure, nausea, and vomiting of 4 h duration. Her medical history included hypertension (treated with metoprolol and ramipril), hyperlipidemia (treated with atorvastatin), and depression (treated with fluoxetine). A few hours before symptom onset, she had witnessed an accident in which her sister sustained serious injuries. The patient was visiting her sister—who was in critical condition in the hospital—when the symptoms began.Investigations. Physical examination, chest radiography, laboratory testing, electrocardiography, coronary angiography, and PET with11C hydroxyephedrine.Diagnosis. Stress-induced (Takotsubo) cardiomyopathy (apical ballooning syndrome).Management. The patient was monitored with cardiac telemetry. Metoprolol and ramipril were continued.

Original languageEnglish (US)
Pages (from-to)430-434
Number of pages5
JournalNature Reviews Cardiology
Issue number6
StatePublished - Jun 2009

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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