Can cervicography be improved? An evaluation with arbitrated cervicography interpretations

Diana L. Schneider; Louis Burke; Thomas C. Wright; Mark Spitzer; Nilanjan Chatterjee; Sholom Wacholder; Rolando Herrero; Maria C. Bratti; Mitchell D. Greenberg; Allan Hildesheim; Mark E. Sherman; Jorge Morales; Martha L. Hutchinson; Mario Alfaro; Attila Lörincz; Mark Schiffman

doi:10.1067/mob.2002.122848

Can cervicography be improved? An evaluation with arbitrated cervicography interpretations

Diana L. Schneider, Louis Burke, Thomas C. Wright, Mark Spitzer, Nilanjan Chatterjee, Sholom Wacholder, Rolando Herrero, Maria C. Bratti, Mitchell D. Greenberg, Allan Hildesheim, Mark E. Sherman, Jorge Morales, Martha L. Hutchinson, Mario Alfaro, Attila Lörincz, Mark Schiffman

Quantitative Health Sciences

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

OBJECTIVE: The purpose of this study was to estimate the optimal performance of cervicography. We compared an arbitrated cervigram classification with an arbitrated referent diagnosis of cervical neoplasia. STUDY DESIGN: From an initial group of 8460 women, a stratified sample of cervigrams from 3645 women and histologic information from 414 women underwent arbitration. Interobserver agreement was assessed for cervicography and the referent diagnosis. Sensitivity, specificity, and predictive values were estimated for initial and arbitrated cervicography results, compared with the initial and arbitrated referent diagnoses. RESULTS: For the detection of arbitrated high-grade lesions or cancer, arbitrated cervicography yielded an overall sensitivity of 63.9% and a specificity of 93.7%. Significantly higher sensitivity was associated with younger age and age-related visual characteristics. CONCLUSION: Optimization of the cervigram classification improved performance over a single interpretation in this population but suggested the limits of static visual screening.

Original language	English (US)
Pages (from-to)	15-23
Number of pages	9
Journal	American journal of obstetrics and gynecology
Volume	187
Issue number	1
DOIs	https://doi.org/10.1067/mob.2002.122848
State	Published - 2002

Keywords

Cervical cancer
Cervical neoplasia
Cervicography
Screening

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1067/mob.2002.122848

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Schneider, D. L., Burke, L., Wright, T. C., Spitzer, M., Chatterjee, N., Wacholder, S., Herrero, R., Bratti, M. C., Greenberg, M. D., Hildesheim, A., Sherman, M. E., Morales, J., Hutchinson, M. L., Alfaro, M., Lörincz, A., & Schiffman, M. (2002). Can cervicography be improved? An evaluation with arbitrated cervicography interpretations. American journal of obstetrics and gynecology, 187(1), 15-23. https://doi.org/10.1067/mob.2002.122848

Schneider, DL, Burke, L, Wright, TC, Spitzer, M, Chatterjee, N, Wacholder, S, Herrero, R, Bratti, MC, Greenberg, MD, Hildesheim, A, Sherman, ME, Morales, J, Hutchinson, ML, Alfaro, M, Lörincz, A & Schiffman, M 2002, 'Can cervicography be improved? An evaluation with arbitrated cervicography interpretations', American journal of obstetrics and gynecology, vol. 187, no. 1, pp. 15-23. https://doi.org/10.1067/mob.2002.122848

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abstract = "OBJECTIVE: The purpose of this study was to estimate the optimal performance of cervicography. We compared an arbitrated cervigram classification with an arbitrated referent diagnosis of cervical neoplasia. STUDY DESIGN: From an initial group of 8460 women, a stratified sample of cervigrams from 3645 women and histologic information from 414 women underwent arbitration. Interobserver agreement was assessed for cervicography and the referent diagnosis. Sensitivity, specificity, and predictive values were estimated for initial and arbitrated cervicography results, compared with the initial and arbitrated referent diagnoses. RESULTS: For the detection of arbitrated high-grade lesions or cancer, arbitrated cervicography yielded an overall sensitivity of 63.9% and a specificity of 93.7%. Significantly higher sensitivity was associated with younger age and age-related visual characteristics. CONCLUSION: Optimization of the cervigram classification improved performance over a single interpretation in this population but suggested the limits of static visual screening.",

keywords = "Cervical cancer, Cervical neoplasia, Cervicography, Screening",

author = "Schneider, {Diana L.} and Louis Burke and Wright, {Thomas C.} and Mark Spitzer and Nilanjan Chatterjee and Sholom Wacholder and Rolando Herrero and Bratti, {Maria C.} and Greenberg, {Mitchell D.} and Allan Hildesheim and Sherman, {Mark E.} and Jorge Morales and Hutchinson, {Martha L.} and Mario Alfaro and Attila L{\"o}rincz and Mark Schiffman",

note = "Funding Information: Supported by the National Cancer Institute, contracts No. N01-CP-21081 and NO 1-CP-31061. ",

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doi = "10.1067/mob.2002.122848",

language = "English (US)",

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AU - Burke, Louis

AU - Wright, Thomas C.

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AU - Chatterjee, Nilanjan

AU - Wacholder, Sholom

AU - Herrero, Rolando

AU - Bratti, Maria C.

AU - Greenberg, Mitchell D.

AU - Hildesheim, Allan

AU - Sherman, Mark E.

AU - Morales, Jorge

AU - Hutchinson, Martha L.

AU - Alfaro, Mario

AU - Lörincz, Attila

AU - Schiffman, Mark

N1 - Funding Information: Supported by the National Cancer Institute, contracts No. N01-CP-21081 and NO 1-CP-31061.

PY - 2002

Y1 - 2002

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AB - OBJECTIVE: The purpose of this study was to estimate the optimal performance of cervicography. We compared an arbitrated cervigram classification with an arbitrated referent diagnosis of cervical neoplasia. STUDY DESIGN: From an initial group of 8460 women, a stratified sample of cervigrams from 3645 women and histologic information from 414 women underwent arbitration. Interobserver agreement was assessed for cervicography and the referent diagnosis. Sensitivity, specificity, and predictive values were estimated for initial and arbitrated cervicography results, compared with the initial and arbitrated referent diagnoses. RESULTS: For the detection of arbitrated high-grade lesions or cancer, arbitrated cervicography yielded an overall sensitivity of 63.9% and a specificity of 93.7%. Significantly higher sensitivity was associated with younger age and age-related visual characteristics. CONCLUSION: Optimization of the cervigram classification improved performance over a single interpretation in this population but suggested the limits of static visual screening.

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KW - Screening

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Can cervicography be improved? An evaluation with arbitrated cervicography interpretations

Abstract

Keywords

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