Can an alternative outflow strategy be utilized for high-risk bridged patients with previous cardiac surgery?

Timothy F. Danish, Mary E. Davis, Meng Xu, Monica Djunaidi, Matthew R. Danter, Sudhir S. Kushwaha, John M. Stulak, Nicholas A. Haglund, Simon Maltais

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The HeartWare ventricular assist device (HVAD) is an implantable continuous-flow centrifugal pump that has allowed the development of sternal-sparing techniques, with the use of alternative outflow strategies. We compared early outcomes for patients bridged with the conventional versus alternative outflow graft strategy. From January 2013 to October 2014, 89 patients with HVAD implantation were identified. Survival was analyzed with Kaplan-Meier methods, and a log-rank test was used to compare outcomes between groups. Thirty patients (34%) had ≥1 previous sternotomy before HVAD implantation. Eight patients (27%) were approached using an alternative outflow graft technique with outflow graft connection to the descending aorta (n = 4, 50%) or left subclavian artery (n = 4, 50%), whereas 22 (73%) were implanted via a conventional sternotomy approach with the outflow graft to the ascending aorta. Preoperative characteristics (age, Interagency Registry for Mechanically Assisted Circulatory Support [INTERMACS], and Lietz-Miller score) were comparable between groups (all p > 0.05). Median follow-up was 4.7 (2.8-9.3) months of support. Outcomes were comparable between conventional and alternative outflow groups; survival at 6 months was 74% for the conventional group and 83% in the alternative outflow group. An alternative outflow graft strategy can be utilized to support bridged patients with a history of prior sternotomy.

Original languageEnglish (US)
Pages (from-to)390-396
Number of pages7
JournalASAIO Journal
Issue number4
StatePublished - Aug 1 2016


  • alternative outflow graft
  • mechanical circulatory support
  • ventricular assist device

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering


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