Calciphylaxis: A cause of necrotic ulcers in renal failure

Amer N. Kalaaji, Margaret C. Douglass, Marsha Chaffins, Lori Lowe

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Background: Calciphylaxis is a rare and life-threatening condition occurring in patients with end-stage renal disease on dialysis. The diagnosis is frequently delayed or missed and therapy is often unsuccessful. Objective: The clinical and pathological components of calciphylaxis are emphasized in a patient that may facilitate early diagnosis and initiation of therapy. Results: Early recognition of the clinical signs and symptoms of calciphylaxis is crucial. The tissue diagnosis requires large elliptical biopsies because histological findings are segmental and often missed. Conclusion: Early diagnosis and intervention in calciphylaxis is critical. Parathyroidectomy should be considered in all cases.

Original languageEnglish (US)
Pages (from-to)242-244
Number of pages3
JournalJournal of Cutaneous Medicine and Surgery
Issue number4
StatePublished - Apr 1998

ASJC Scopus subject areas

  • Surgery
  • Dermatology


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