Breast feeding and the development of juvenile rheumatoid arthritis

T. Mason, C. E. Rabinovich, D. D. Fredrickson, K. Amoroso, A. M. Reed, L. D. Stein, B. W. Kredich

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Objective. To determine if children with juvenile rheumatoid arthritis (JRA) are less likely to have been breast fed than controls. Methods. Case-control study of data obtained from a survey of mothers of 54 children with JRA and 79 playmates regarding breast feeding. Duration of breast feeding was tabulated and odds ratios (OR) with 95% confidence intervals (CI) were determined. Results. OR for breast feeding in children with JRA was 0.40 (0.20-0.81, 95% CI) compared to playmates. For pauciarticular JRA (N = 28) OR was 0.31 (0.10-0.93); in polyarticular JRA (N = 24) OR was 0.60 (0.21-1.70). Lower OR for increased durations of breast feeding were noted in children with JRA. Conclusion. Children who have had JRA, especially pauciarticular JRA, are less likely to have been breast fed than controls, suggesting that breast feeding may have a protective effect on the development of JRA.

Original languageEnglish (US)
Pages (from-to)1166-1170
Number of pages5
JournalJournal of Rheumatology
Issue number6
StatePublished - 1995


  • breast feeding
  • childhood
  • juvenile rheumatoid arthritis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology


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