Brain tumor-related epilepsy

Anteneh M. Feyissa

doi:10.1007/978-3-030-59078-9_14

Brain tumor-related epilepsy

Anteneh M. Feyissa

Neurology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Epileptic seizures often develop in patients with a brain tumor (40-100%), and approximately 30% of patients are drug-resistant even after resection. The incidence is higher in low-grade glial tumors located in the frontal and temporo-insular regions. Management of brain tumor-related epilepsy involves the use of anti-seizure medications, surgical resection, and adjuvant chemoradiation. Gross-total tumor resection, including the peritumoral epileptogenic zone, provides the highest chance of seizure freedom. Intraoperative electrocorticography is being increasingly utilized to identify the location and limits of the epileptogenic zone, guide the extent of resection, and map eloquent cortex during brain tumor surgeries.

Original language	English (US)
Title of host publication	Epilepsy Case Studies
Subtitle of host publication	Pearls for Patient Care: Second Edition
Publisher	Springer International Publishing
Pages	77-80
Number of pages	4
ISBN (Electronic)	9783030590789
ISBN (Print)	9783030590772
DOIs	https://doi.org/10.1007/978-3-030-59078-9_14
State	Published - Dec 19 2020

Keywords

Brain tumor
Cortical mapping
Electrocorticography
Epilepsy surgery
Epileptogenesis
Glioma
Seizure

ASJC Scopus subject areas

General Medicine

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10.1007/978-3-030-59078-9_14

Cite this

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AB - Epileptic seizures often develop in patients with a brain tumor (40-100%), and approximately 30% of patients are drug-resistant even after resection. The incidence is higher in low-grade glial tumors located in the frontal and temporo-insular regions. Management of brain tumor-related epilepsy involves the use of anti-seizure medications, surgical resection, and adjuvant chemoradiation. Gross-total tumor resection, including the peritumoral epileptogenic zone, provides the highest chance of seizure freedom. Intraoperative electrocorticography is being increasingly utilized to identify the location and limits of the epileptogenic zone, guide the extent of resection, and map eloquent cortex during brain tumor surgeries.

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KW - Cortical mapping

KW - Electrocorticography

KW - Epilepsy surgery

KW - Epileptogenesis

KW - Glioma

KW - Seizure

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Brain tumor-related epilepsy

Abstract

Keywords

ASJC Scopus subject areas

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