Brain tumor and epilepsy

Gregory D. Cascino, William O. Tatum

Research output: Chapter in Book/Report/Conference proceedingChapter


A 30-year-old patient had a 3- to 4-year history of recurrent focal seizures. He was diagnosed with localization-related epilepsy manifested as recurrent focal seizures associated with a sudden behavioral arrest, vacant stare, and right upper extremity dystonic posturing. The duration was brief and was associated with postictal amnesia and word-finding difficulties. Rare nocturnal generalized tonic-clonic seizures also occurred. His neurological examination was unremarkable except for the mental status testing that demonstrated abnormal short-term memory. Routine EEG shows bitemporal epileptiform discharges which were most prevalent on the left during sleep. A CT of the brain was normal. The patient's seizures were refractory to phenytoin, carbamazepine, lamotrigine, and levetiracetam. MRI brain showed a focal lesion in the left medial temporal lobe (Fig. 12.1). The appearance suggested a primary brain tumor.

Original languageEnglish (US)
Title of host publicationEpilepsy Case Studies
Subtitle of host publicationPearls for Patient Care
PublisherSpringer International Publishing
Number of pages4
ISBN (Electronic)9783319013664
ISBN (Print)3319013653, 9783319013657
StatePublished - Nov 1 2014

ASJC Scopus subject areas

  • General Medicine


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