Brain Stimulation in Childhood Mental Health: Therapeutic Applications.

F. P. MacMaster, M. Sembo, K. Ma, P. Croarkin

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


The treatment of pediatric mental illness and neurodevelopmental disorders faces two considerable obstacles. First, few new medications are in development and second, existing treatments are often limited in effectiveness and tolerability in this age group. Transcranial magnetic stimulation (TMS) and transcranial direct-current stimulation (tDCS) are types of non-invasive brain stimulation with promise as brain-based interventions for mental illness and neurodevelopmental disorders. TMS and tDCS have considerable advantages in children and adolescents, such as a strong safety profile, short duration to clinical effect, and durability of effects. Most importantly, brain stimulation requires the identification of a biologic target. As such, therapeutic research has the prospect of advancing the pathophysiologic understanding of neuropsychiatric illnesses. Evidence supports the need for larger studies of TMS in major depressive disorder (MDD), particularly in the developing brain. Future research may support the use of brain stimulation in autism spectrum disorders, attention-deficit hyperactivity disorder, childhood-onset schizophrenia, and Tourette syndrome.

Original languageEnglish (US)
Title of host publicationPediatric Brain Stimulation
Subtitle of host publicationMapping and Modulating The Developing Brain
PublisherElsevier Inc.
Number of pages24
ISBN (Electronic)9780128020388
ISBN (Print)9780128020012
StatePublished - May 17 2016


  • Adolescents
  • Attention deficit hyperactivity disorder
  • Autistic spectrum disorder
  • Brain stimulation
  • Childhood-onset schizophrenia
  • Children
  • Depression
  • Tourette syndrome

ASJC Scopus subject areas

  • General Neuroscience


Dive into the research topics of 'Brain Stimulation in Childhood Mental Health: Therapeutic Applications.'. Together they form a unique fingerprint.

Cite this