Brain Injury in the Preterm and Term Neonate

Mai Lan Ho, Alice C. Patton, David R. DeLone, Hosung Kim, Julie R. Gilbertson, Joel Felmlee, Robert E. Watson

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Neonatal brain injury results from a complex interplay of maternal and perinatal factors, and can be challenging to diagnose from both clinical and radiologic perspectives. Depending on infant age and severity of insult, various types of brain injury can result. We will discuss the benefits and disadvantages of different imaging modalities: US, CT, MRI, PET, and SPECT. Focusing on MRI, we will discuss special considerations for neonates, including clinical stabilization, technical challenges, and advanced imaging approaches such as ASL, MRS, and SWI. In the remainder of the article, we will review the pathophysiology and MR imaging patterns of brain injury in preterm and term infants.

Original languageEnglish (US)
Article number39
JournalCurrent Radiology Reports
Issue number7
StatePublished - Jul 1 2016


  • Computed tomography
  • Hypoxic-ischemic encephalopathy
  • Neonatal imaging
  • Preterm brain injury
  • Term brain injury
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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