Bone marrow dendritic cell aggregates associate with systemic immune dysregulation in chronic myelomonocytic leukemia

Abhishek A. Mangaonkar; Kaaren K. Reichard; Moritz Binder; Giacomo Coltro; Terra L. Lasho; Ryan M. Carr; April Chiu; Vivian Negron; Mehrdad Hefazi; Theodora Anagnostou; Michael M. Timm; James W. Hiebert; Jose C. Villasboas; Wilson I. Gonsalves; Naseema Gangat; Mithun Shah; Hassan B. Alkhateeb; Aref Al-Kali; Michelle A. Elliott; Kebede H. Begna; Alexandra P. Wolanskyj-Spinner; Mark R. Litzow; William J. Hogan; Stephen M. Ansell; Animesh Pardanani; Ayalew Tefferi; Mrinal M. Patnaik

doi:10.1182/bloodadvances.2020002415

Bone marrow dendritic cell aggregates associate with systemic immune dysregulation in chronic myelomonocytic leukemia

Abhishek A. Mangaonkar, Kaaren K. Reichard, Moritz Binder, Giacomo Coltro, Terra L. Lasho, Ryan M. Carr, April Chiu, Vivian Negron, Mehrdad Hefazi, Theodora Anagnostou, Michael M. Timm, James W. Hiebert, Jose C. Villasboas, Wilson I. Gonsalves, Naseema Gangat, Mithun Shah, Hassan B. Alkhateeb, Aref Al-Kali, Michelle A. Elliott, Kebede H. BegnaAlexandra P. Wolanskyj-Spinner, Mark R. Litzow, William J. Hogan, Stephen M. Ansell, Animesh Pardanani, Ayalew Tefferi, Mrinal M. Patnaik

Hematology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Original language	English (US)
Pages (from-to)	5425-5430
Number of pages	6
Journal	Blood Advances
Volume	4
Issue number	21
DOIs	https://doi.org/10.1182/bloodadvances.2020002415
State	Published - Nov 10 2020

ASJC Scopus subject areas

Hematology

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Mangaonkar, A. A., Reichard, K. K., Binder, M., Coltro, G., Lasho, T. L., Carr, R. M., Chiu, A., Negron, V., Hefazi, M., Anagnostou, T., Timm, M. M., Hiebert, J. W., Villasboas, J. C., Gonsalves, W. I., Gangat, N., Shah, M., Alkhateeb, H. B., Al-Kali, A., Elliott, M. A., ... Patnaik, M. M. (2020). Bone marrow dendritic cell aggregates associate with systemic immune dysregulation in chronic myelomonocytic leukemia. Blood Advances, 4(21), 5425-5430. https://doi.org/10.1182/bloodadvances.2020002415

Mangaonkar, AA, Reichard, KK, Binder, M, Coltro, G, Lasho, TL, Carr, RM, Chiu, A, Negron, V, Hefazi, M, Anagnostou, T, Timm, MM, Hiebert, JW, Villasboas, JC , Gonsalves, WI, Gangat, N, Shah, M, Alkhateeb, HB, Al-Kali, A, Elliott, MA, Begna, KH, Wolanskyj-Spinner, AP, Litzow, MR , Hogan, WJ , Ansell, SM , Pardanani, A , Tefferi, A & Patnaik, MM 2020, 'Bone marrow dendritic cell aggregates associate with systemic immune dysregulation in chronic myelomonocytic leukemia', Blood Advances, vol. 4, no. 21, pp. 5425-5430. https://doi.org/10.1182/bloodadvances.2020002415

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title = "Bone marrow dendritic cell aggregates associate with systemic immune dysregulation in chronic myelomonocytic leukemia",

author = "Mangaonkar, {Abhishek A.} and Reichard, {Kaaren K.} and Moritz Binder and Giacomo Coltro and Lasho, {Terra L.} and Carr, {Ryan M.} and April Chiu and Vivian Negron and Mehrdad Hefazi and Theodora Anagnostou and Timm, {Michael M.} and Hiebert, {James W.} and Villasboas, {Jose C.} and Gonsalves, {Wilson I.} and Naseema Gangat and Mithun Shah and Alkhateeb, {Hassan B.} and Aref Al-Kali and Elliott, {Michelle A.} and Begna, {Kebede H.} and Wolanskyj-Spinner, {Alexandra P.} and Litzow, {Mark R.} and Hogan, {William J.} and Ansell, {Stephen M.} and Animesh Pardanani and Ayalew Tefferi and Patnaik, {Mrinal M.}",

note = "Funding Information: The authors acknowledge the services and expertise of the Pathology Research Core, the Immune Monitoring Core, and the Metabolomics Resource Core of Mayo Clinic (Rochester, MN). The authors also acknowledge the technical input of Hyo Jin Kim for the flow cytometry experiments. This work was supported, in part, by the American Society of Clinical Oncology Conquer Cancer Foundation–sponsored Young Investigator Award, the Eagles 5th District Cancer Telethon Pilot Investigator Award, and the Mayo Clinic Hematology Small Grants Program Grant (A.A.M.), as well as grant UL1TR002377 from the National Institutes of Health, National Center for Advancing Translational Sciences. Results and views do not necessarily reflect the views of the funding agencies. Funding Information: This work was supported, in part, by the American Society of Clinical Oncology Conquer Cancer Foundation–sponsored Young",

year = "2020",

month = nov,

day = "10",

doi = "10.1182/bloodadvances.2020002415",

language = "English (US)",

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T1 - Bone marrow dendritic cell aggregates associate with systemic immune dysregulation in chronic myelomonocytic leukemia

AU - Mangaonkar, Abhishek A.

AU - Reichard, Kaaren K.

AU - Binder, Moritz

AU - Coltro, Giacomo

AU - Lasho, Terra L.

AU - Carr, Ryan M.

AU - Chiu, April

AU - Negron, Vivian

AU - Hefazi, Mehrdad

AU - Anagnostou, Theodora

AU - Timm, Michael M.

AU - Hiebert, James W.

AU - Villasboas, Jose C.

AU - Gonsalves, Wilson I.

AU - Gangat, Naseema

AU - Shah, Mithun

AU - Alkhateeb, Hassan B.

AU - Al-Kali, Aref

AU - Elliott, Michelle A.

AU - Begna, Kebede H.

AU - Wolanskyj-Spinner, Alexandra P.

AU - Litzow, Mark R.

AU - Hogan, William J.

AU - Ansell, Stephen M.

AU - Pardanani, Animesh

AU - Tefferi, Ayalew

AU - Patnaik, Mrinal M.

N1 - Funding Information: The authors acknowledge the services and expertise of the Pathology Research Core, the Immune Monitoring Core, and the Metabolomics Resource Core of Mayo Clinic (Rochester, MN). The authors also acknowledge the technical input of Hyo Jin Kim for the flow cytometry experiments. This work was supported, in part, by the American Society of Clinical Oncology Conquer Cancer Foundation–sponsored Young Investigator Award, the Eagles 5th District Cancer Telethon Pilot Investigator Award, and the Mayo Clinic Hematology Small Grants Program Grant (A.A.M.), as well as grant UL1TR002377 from the National Institutes of Health, National Center for Advancing Translational Sciences. Results and views do not necessarily reflect the views of the funding agencies. Funding Information: This work was supported, in part, by the American Society of Clinical Oncology Conquer Cancer Foundation–sponsored Young

PY - 2020/11/10

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JO - Blood Advances

JF - Blood Advances

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ER -

Bone marrow dendritic cell aggregates associate with systemic immune dysregulation in chronic myelomonocytic leukemia

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